Background Congenital disorders of glycosylation (CDG) are inherited metabolic diseases
caused by defects in the genes important for the process of protein and lipid glycosylation …

Congenital disorders of glycosylation (CDG) are a group of more than 160 inborn errors of
metabolism affecting multiple pathways of protein and lipid glycosylation. Patients present …

FUT8 is an essential α-1, 6-fucosyltransferase that fucosylates the innermost GlcNAc of N-
glycans, a process called core fucosylation. In vitro, FUT8 exhibits substrate preference for …

N-glycosylation is a highly conserved glycan modification, and more than 7000 proteins are
N-glycosylated in humans. N-glycosylation has many biological functions such as protein …

This review is the tenth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

Congenital disorders of glycosylation are a genetically and phenotypically heterogeneous
family of diseases affecting the co‐and posttranslational modification of proteins. Using …

Despite advances in the identification and diagnosis of congenital disorders of glycosylation
(CDG), treatment options remain limited and are often constrained to symptomatic …

Mammalian Asn-linked glycans are extensively processed as they transit the secretory
pathway to generate diverse glycans on cell surface and secreted glycoproteins. Additional …

Fucosylation is essential for intercellular and intracellular recognition, cell‐cell interaction,
fertilization, and inflammatory processes. Only five types of congenital disorders of …

The present study explored the impact of inhibiting α (1, 6) fucosylation (core fucosylation)
on the functional phenotype of a cellular model of colorectal cancer (CRC) malignization …