Beyond small molecules: advancing MYC-targeted cancer therapies through protein engineering

R Edaibis, R Akel, JA Shin - Transcription, 2025 - Taylor & Francis
Protein engineering has emerged as a powerful approach toward the development of novel
therapeutics targeting the MYC/MAX/E-box network, an active driver of> 70% of cancers …

Assembling Branched and Macrocyclic Peptides on Proteins

S Ullrich, S Kumaresan, MG Rahman… - Chemical …, 2025 - pubs.rsc.org
A two-step, biocompatible strategy enables site-specific generation of branched and
macrocyclic peptide–protein conjugates. Surface-exposed cysteines on proteins are …

[引用][C] Targeting MYC with protein drugs

JA Shin - 2024 - Elsevier