The chronic lung diseases, asthma and chronic obstructive pulmonary disease (COPD), are
common affecting over 500 million people worldwide and causing substantial morbidity and …

Asthma | From Bronchoconstriction to Airways Inflammation and Remodeling | American
Journal of Respiratory and Critical Care Medicine ATS Journals Logo Official Publications …

Background Tezepelumab is a human monoclonal antibody that blocks the activity of thymic
stromal lymphopoietin (TSLP), an epithelial cell-derived cytokine. In phase 2b and 3 studies …

The Intervention Mapping bible, updated with new theory, trends, and cases Planning
Health Promotion Programs is the" bible" of the field, guiding students and practitioners …

The common disease asthma is probably not a single disease, but rather a complex of
multiple, separate syndromes that overlap. Although clinicians have recognised these …

Background Chronic obstructive pulmonary disease (COPD) is associated with eosinophilic
airway inflammation in 10–20% of patients. Benralizumab, an anti-interleukin-5 receptor α …

While asthma is considered an inflammatory disorder of the conducting airways, it is
becoming increasingly apparent that the disease is heterogeneous with respect to …

Background: Although inhaled corticosteroids have an established role in the treatment of
asthma, studies have tended to concentrate on non-smokers and little is known about the …

The role of inflammation in the pathogenesis of severe asthma chronically treated with high
doses of glucocorticoids is poorly understood. Despite this, treatment has been aimed at …

IgE plays an important role in allergic asthma. We hypothesized that reducing IgE in the
airway mucosa would reduce airway inflammation. Forty-five patients with mild to moderate …