Cilta-cel, a BCMA-targeting CAR-T therapy for patients with multiple myeloma

S Jagannath, CC Jackson, JM Schecter… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Ciltacabtagene autoleucel (cilta-cel), a BCMA-targeting CAR-T therapy, is
approved in the United States and Europe for patients with relapsed/refractory multiple …

Development and validation of a prediction model of outcome after B-cell maturation antigen-directed chimeric antigen receptor T-cell therapy in relapsed/refractory …

N Gagelmann, D Dima, M Merz, H Hashmi… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE Although chimeric antigen receptor T therapy (CAR-T) cells are an established
therapy for relapsed/refractory multiple myeloma (RRMM), there are no established models …

CAR T-cell therapy to treat multiple myeloma: current state and future directions

ST Reddy, H Hosoya, L Mikkilineni - Cancer and Metastasis Reviews, 2025 - Springer
Chimeric antigen receptor (CAR) T-cell therapy represents a transformative advancement in
treating relapsed or refractory multiple myeloma (MM) in both early-and late-line settings …

[HTML][HTML] Absolute lymphocyte count and outcomes of multiple myeloma patients treated with idecabtagene vicleucel: the us myeloma immunotherapy consortium real …

J Khouri, D Dima, H Li, D Hansen, S Sidana… - … and Cellular Therapy, 2024 - Elsevier
Idecabtagene vicleucel (ide-cel) has shown impressive efficacy in relapsed/refractory
multiple myeloma (RRMM). This study aimed to investigate the impact of absolute …

Current Novel Targeted Therapeutic Strategies in Multiple Myeloma

CHT Lin, MJ Tariq, F Ullah, A Sannareddy… - International Journal of …, 2024 - mdpi.com
Multiple myeloma (MM) is a hematologic malignancy caused by the clonal expansion of
immunoglobulin-producing plasma cells in the bone marrow and/or extramedullary sites …

[HTML][HTML] Plasma Cell Neoplasms with Spreading in the Blood and Tissues: Extramedullary Myeloma Disease, a Rare Aggressive Form of Multiple Myeloma (First of …

U Testa, G Leone - Mediterranean Journal of Hematology and …, 2025 - pmc.ncbi.nlm.nih.gov
Multiple myeloma is a disease related to the proliferation of malignant plasma cells; in most
patients, the disease is confined to the level of bone marrow. However, in a minority of …

[HTML][HTML] Outcomes of Idecabtagene Vicleucel Therapy in Patients with Relapsed/Refractory Multiple Myeloma: A Single-Institution Experience

A Trando, F Ghamsari, P Yeung, C Costello, I Saunders… - Biomedicines, 2024 - mdpi.com
Background/Objectives: Idecabtagene vicleucel (ide-cel), an anti-B-cell maturation chimeric
antigen receptor T-cell therapy, represents an unprecedented treatment option for …

CAR-T cell therapy in relapsed or refractory multiple myeloma and access in Turkey

G Hakan, K Engin, KA Elifcan, D Haluk… - Frontiers in …, 2024 - frontiersin.org
The past decade has seen the development of immunotherapy for the treatment of multiple
myeloma (MM), beginning with monoclonal antibodies (mAbs) in the relapsed and refractory …

[HTML][HTML] ASTCT Committee on Practice Guidelines Survey on Evaluation and Management of Relapsed/Refractory Multiple Myeloma after Failure of Chimeric Antigen …

H Hashmi, A Kumar, MA Kharfan-Dabaja… - … and Cellular Therapy, 2024 - Elsevier
Chimeric antigen receptor T cell therapy (CAR-T) has revolutionized the management of
relapsed and/or refractory multiple myeloma (RRMM). However, CAR-T treatment failure is …

Efficacy and safety of teclistamab in relapsed or refractory multiple myeloma: a systematic review and meta-analysis

Z Qureshi, A Jamil, F Altaf, R Siddique, F Ahmed - Annals of Hematology, 2024 - Springer
To synthesize the evidence on the efficacy and safety of teclistamab in treating
relapsed/refractory multiple myeloma (RRMM). A systematic search for records published …