[HTML][HTML] Metabolism and function of coenzyme Q

M Turunen, J Olsson, G Dallner - Biochimica et Biophysica Acta (BBA) …, 2004 - Elsevier
Coenzyme Q (CoQ) is present in all cells and membranes and in addition to be a member of
the mitochondrial respiratory chain it has also several other functions of great importance for …

Role of mitochondria in oxidative stress and aging

G Lenaz, C Bovina, M D'aurelio, R Fato… - Annals of the New …, 2002 - Wiley Online Library
The mitochondrial respiratory chain is a powerful source of reactive oxygen species (ROS),
considered as the pathogenic agent of many diseases and of aging. We have investigated …

Cold atmospheric plasma jet-generated RONS and their selective effects on normal and carcinoma cells

SJ Kim, TH Chung - Scientific reports, 2016 - nature.com
Cold atmospheric helium plasma jets were fabricated and utilized for plasma–cell
interactions. The effect of operating parameters and jet design on the generation of specific …

A “mitochondrial cascade hypothesis” for sporadic Alzheimer's disease

RH Swerdlow, SM Khan - Medical hypotheses, 2004 - Elsevier
Alzheimer's disease (AD) includes etiologically heterogenous disorders characterized by
senile or presenile dementia, extracellular amyloid protein aggregations containing an …

Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging

DH Hyun, SS Emerson, DG Jo… - Proceedings of the …, 2006 - National Acad Sciences
The plasma membrane (PM) contains redox enzymes that provide electrons for energy
metabolism and recycling of antioxidants such as coenzyme Q and α-tocopherol. Brain …

Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging

Z Ungvari, C Parrado-Fernandez, A Csiszar… - Circulation …, 2008 - Am Heart Assoc
This review focuses on the emerging evidence that attenuation of the production of reactive
oxygen species and inhibition of inflammatory pathways play a central role in the antiaging …

Reactive oxygen species in spermatozoa: methods for monitoring and significance for the origins of genetic disease and infertility

MA Baker, RJ Aitken - Reproductive biology and endocrinology, 2005 - Springer
Human spermatozoa generate low levels of reactive oxygen species in order to stimulate
key events, such as tyrosine phosphorylation, associated with sperm capacitation. However …

[HTML][HTML] Cell surface oxygen consumption: a major contributor to cellular oxygen consumption in glycolytic cancer cell lines

PM Herst, MV Berridge - Biochimica et Biophysica Acta (BBA) …, 2007 - Elsevier
Oxygen consumption for bioenergetic purposes has long been thought to be the prerogative
of mitochondria. Nevertheless, mitochondrial gene knockout (ρ0) cells that are defective in …

The importance of plasma membrane coenzyme Q in aging and stress responses

P Navas, JM Villalba, R de Cabo - Mitochondrion, 2007 - Elsevier
The plasma membrane of eukaryotic cells is the limit to interact with the environment. This
position implies receiving stress signals that affects its components such as phospholipids …

Efficacy of beta-lapachone in pancreatic cancer treatment: exploiting the novel, therapeutic target NQO1

M Ough, A Lewis, EA Bey, J Gao, JM Ritchie… - Cancer biology & …, 2005 - Taylor & Francis
NAD (P) H: quinone oxidoreductase (NQO1) is elevated in human pancreatic cancers. We
hypothesized that£]-lapachone, a novel 1, 2-naphthoquinone with potential antitumor activity …