Tetraspanins are a family of proteins with four transmembrane domains that play a role in
many aspects of cell biology and physiology; they are also used by several pathogens for …

Cell-surface proteins of the tetraspanin family are small, and often hidden by a canopy of tall
glycoprotein neighbours in the cell membrane. Consequently, tetraspanins have been …

Exosomes are 40–100nm extracellular vesicles that are released from a multitude of cell
types, and perform diverse cellular functions including intercellular communication, antigen …

Tetraspanins play critical roles in various physiological processes, ranging from cell
adhesion to virus infection. The members of the tetraspanin family have four membrane …

Exosomes are membrane vesicles released into the extracellular environment upon exocytic
fusion of multivesicular endosomes with the cell surface. They have a particular composition …

Exosomes are 60–100-nm membrane vesicles that are secreted into the extracellular milieu
as a consequence of multivesicular body fusion with the plasma membrane. Here we …

Exosomes are membrane vesicles with a diameter of 40–100 nm that are secreted by many
cell types into the extracellular milieu. They correspond to the internal vesicles of an …

Membrane lipids and proteins are non-randomly distributed and are unable to diffuse freely
in the plane of the membrane. This is because of multiple constraints imposed both by the …

▪ Abstract This review summarizes key aspects of tetraspanin proteins, with a focus on the
functional relevance and structural features of these proteins and how they are organized …

Tumours progress through a cascade of events that enable the formation of metastases.
Some of the components that are required for this fatal process are well established …