Amyotrophic lateral sclerosis

EL Feldman, SA Goutman, S Petri, L Mazzini… - The Lancet, 2022 - thelancet.com
Amyotrophic lateral sclerosis is a fatal CNS neurodegenerative disease. Despite intensive
research, current management of amyotrophic lateral sclerosis remains suboptimal from …

Emerging insights into the complex genetics and pathophysiology of amyotrophic lateral sclerosis

SA Goutman, O Hardiman, A Al-Chalabi… - The Lancet …, 2022 - thelancet.com
Amyotrophic lateral sclerosis is a fatal neurodegenerative disease. The discovery of genes
associated with amyotrophic lateral sclerosis, commencing with SOD1 in 1993, started fairly …

The amyotrophic lateral sclerosis exposome: recent advances and future directions

SA Goutman, MG Savelieff, DG Jang, J Hur… - Nature Reviews …, 2023 - nature.com
Amyotrophic lateral sclerosis (ALS) is a fatal disease of motor neuron degeneration with
typical survival of only 2–5 years from diagnosis. The causes of ALS are multifactorial …

Association between urban greenspace and health: a systematic review of literature

V Gianfredi, M Buffoli, A Rebecchi, R Croci… - International journal of …, 2021 - mdpi.com
The current review aimed to explore the association between urban greenspaces and health
indicators. In particular, our aims were to analyze the association between publicly …

[HTML][HTML] Pesticide exposures for residents living close to agricultural lands: A review

C Dereumeaux, C Fillol, P Quenel, S Denys - Environment international, 2020 - Elsevier
Background Residents living close to agricultural lands might be exposed to pesticides
through non-occupational pathways including spray drift and volatilization of pesticides …

Pesticides, cognitive functions and dementia: A review

AM Aloizou, V Siokas, C Vogiatzi, E Peristeri… - Toxicology letters, 2020 - Elsevier
Pesticides are widely-used chemicals commonly applied in agriculture for the protection of
crops from pests. Depending on the class of pesticides, the specific substances may have a …

Pesticides at brain borders: Impact on the blood-brain barrier, neuroinflammation, and neurological risk trajectories

N Cresto, I Forner-Piquer, A Baig, M Chatterjee… - Chemosphere, 2023 - Elsevier
Pesticides are omnipresent, and they pose significant environmental and health risks.
Translational studies indicate that acute exposure to high pesticide levels is detrimental, and …

Oxidative stress in amyotrophic lateral sclerosis: synergy of genetic and environmental factors

A Motataianu, G Serban, L Barcutean… - International Journal of …, 2022 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a grievous neurodegenerative disease whose survival
is limited to only a few years. In spite of intensive research to discover the underlying …

Environmental and occupational risk factors of amyotrophic lateral sclerosis: a population-based case-control study

T Filippini, M Tesauro, M Fiore, C Malagoli… - International journal of …, 2020 - mdpi.com
Objectives: Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative
disease with still unknown etiology. We aimed at investigating the association between …

[HTML][HTML] Residential exposure to magnetic fields from high-voltage power lines and risk of childhood leukemia

C Malagoli, M Malavolti, LA Wise, E Balboni… - Environmental …, 2023 - Elsevier
Background Several studies have suggested an excess risk of leukemia among children
living close to high-voltage power lines and exposed to magnetic fields. However, not all …