Advanced and biomedical applications of Schiff-base ligands and their metal complexes: A review

A Soroceanu, A Bargan - Crystals, 2022 - mdpi.com
Because of their importance in a variety of interdisciplinary study domains, Schiff-base
ligands have performed a significant role in the evolution of contemporary coordination …

Isatin derivatives and their anti-bacterial activities

H Guo - European Journal of Medicinal Chemistry, 2019 - Elsevier
Bacterial infections are account for the majority of hospital-acquired and community-
acquired infections. The emergency and widespread of drug-resistant pathogens has further …

Recent applications of hydantoin and thiohydantoin in medicinal chemistry

SH Cho, SH Kim, D Shin - European journal of medicinal chemistry, 2019 - Elsevier
Abstract Hydantoin, imidazolidine-2, 4-dione, is a non-aromatic five-membered heterocycle,
which is considered a valuable, privileged scaffold in medicinal chemistry. The importance …

Recent advances in the synthesis of hydantoins: the state of the art of a valuable scaffold

L Konnert, F Lamaty, J Martinez, E Colacino - Chemical Reviews, 2017 - ACS Publications
The review highlights the hydantoin syntheses presented from the point of view of the
preparation methods. Novel synthetic routes to various hydantoin structures, the advances …

Isatin containing heterocycles for different biological activities: Analysis of structure activity relationship

R Nath, S Pathania, G Grover, MJ Akhtar - Journal of Molecular Structure, 2020 - Elsevier
Isatin has been widely used in drug discovery. The ring is part of many naturally occurring
compounds and is used to design compounds with diverse biological activities. These isatin …

A mini review on isatin, an anticancer scaffold with potential activities against neglected tropical diseases (NTDs)

S Chowdhary, Shalini, A Arora, V Kumar - Pharmaceuticals, 2022 - mdpi.com
Isatin, chemically an indole-1 H-2, 3-dione, is recognised as one of the most attractive
therapeutic fragments in drug design and development. The template has turned out to be …

Application of novel Fe3O4/Zn-metal organic framework magnetic nanostructures as an antimicrobial agent and magnetic nanocatalyst in the synthesis of …

BS Bashar, HA Kareem, YM Hasan, N Ahmad… - Frontiers in …, 2022 - frontiersin.org
Using the microwave-assisted method, novel Fe3O4/Zn-metal organic framework magnetic
nanostructures were synthesized. The crystallinity, thermal stability, adsorption/desorption …

Development of novel isatin–nicotinohydrazide hybrids with potent activity against susceptible/resistant Mycobacterium tuberculosis and bronchitis causing–bacteria

ZM Elsayed, WM Eldehna, MM Abdel-Aziz… - Journal of enzyme …, 2021 - Taylor & Francis
Joining the global fight against Tuberculosis, the world's most deadly infectious disease,
herein we present the design and synthesis of novel isatin-nicotinohydrazide hybrids (5a–m …

Design, syntheses, theoretical calculations, MM-GBSA, potential anti-cancer and enzyme activities of novel Schiff base compounds

H Yalazan, D Koç, F Aydın Kose… - Journal of …, 2024 - Taylor & Francis
In this study, new Schiff base compounds (SB-F-OH, SB-Cl-OH and SB-Br-OH) were derived
from chalcone-derived amine compounds containing halogen groups and 4 …

Synthesis and antitumor activity of some new pyrazolo [1, 5-a] pyrimidines

AS Hassan, MF Mady, HM Awad, TS Hafez - Chinese Chemical Letters, 2017 - Elsevier
Abstract New series of pyrazolo [1, 5-a] pyrimidine derivatives 7a–i, 11a–c and Schiff bases
13a–c were synthesized and screened for their in vitro antitumor activity against three …