EMT factors and metabolic pathways in cancer

I Georgakopoulos-Soares, DV Chartoumpekis… - Frontiers in …, 2020 - frontiersin.org
The epithelial-mesenchymal transition (EMT) represents a biological program during which
epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is …

[HTML][HTML] Interplay between microRNAs and WNT/β-catenin signalling pathway regulates epithelial–mesenchymal transition in cancer

NM Ghahhari, S Babashah - European journal of cancer, 2015 - Elsevier
The WNT/β-catenin signalling implies its significance in maintaining an epithelial cell
phenotype, proper cell–cell junctions, and tissue homeostasis. Dysregulation of the …

RETRACTED ARTICLE: Upregulation of long noncoding RNA ZEB1-AS1 promotes tumor metastasis and predicts poor prognosis in hepatocellular carcinoma

T Li, J Xie, C Shen, D Cheng, Y Shi, Z Wu, X Deng… - Oncogene, 2016 - nature.com
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality
worldwide. Despite progress in diagnostics and treatment of HCC, its prognosis remains …

Dysregulation of p53-RBM25-mediated circAMOTL1L biogenesis contributes to prostate cancer progression through the circAMOTL1L-miR-193a-5p-Pcdha pathway

Z Yang, CB Qu, Y Zhang, WF Zhang, DD Wang… - Oncogene, 2019 - nature.com
Abstract p53, circRNAs and miRNAs are important components of the regulatory network
that activates the EMT program in cancer metastasis. In prostate cancer (PCa), however, it …

Impact of vimentin on regulation of cell signaling and matrix remodeling

Z Ostrowska-Podhorodecka, I Ding… - Frontiers in Cell and …, 2022 - frontiersin.org
Vimentin expression contributes to cellular mechanoprotection and is a widely recognized
marker of fibroblasts and of epithelial-mesenchymal transition. But it is not understood how …

Notch signaling and EMT in non-small cell lung cancer: biological significance and therapeutic application

X Yuan, H Wu, N Han, H Xu, Q Chu, S Yu… - Journal of hematology & …, 2014 - Springer
Through epithelial-mesenchymal transition (EMT), cancer cells acquire enhanced ability of
migration and invasion, stem cell like characteristics and therapeutic resistance. Notch …

Epithelial-to-mesenchymal plasticity of cancer stem cells: therapeutic targets in hepatocellular carcinoma

A Jayachandran, B Dhungel, JC Steel - Journal of hematology & oncology, 2016 - Springer
Hepatocellular carcinoma (HCC) remains one of the most common and lethal malignancies
worldwide despite the development of various therapeutic strategies. A better understanding …

Long non-coding RNAs and cancer metastasis: Molecular basis and therapeutic implications

H Ming, B Li, L Zhou, A Goel, C Huang - Biochimica et Biophysica Acta …, 2021 - Elsevier
Cancer metastasis, defined by the epithelial to mesenchymal transition (EMT) of tumor cells,
disseminates from the primary site to progressively colonize in distant tissues, and accounts …

[HTML][HTML] The crosstalk between lncRNA and microRNA in cancer metastasis: orchestrating the epithelial-mesenchymal plasticity

M Cao, Y Jiang, Y Tang, X Liang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Noncoding RNAs (ncRNAs) have been demonstrated to closely associate with gene
regulation and encompass the well-known microRNAs (miRNAs), as well as the most …

Long non‐coding RNA urothelial cancer‐associated 1 promotes bladder cancer cell migration and invasion by way of the hsa‐miR‐145–ZEB 1/2–FSCN 1 pathway

M Xue, H Pang, X Li, H Li, J Pan, W Chen - Cancer science, 2016 - Wiley Online Library
Numerous studies suggest that several long non‐coding RNA s (lnc RNA s) play critical
roles in bladder cancer development and progression. Long non‐coding RNA urothelial …