In light of breathing: environmental light is an important modulator of breathing with clinical implications

AA Jones, DM Arble - Frontiers in Neuroscience, 2023 - frontiersin.org
In vertebrate animals, the automatic, rhythmic pattern of breathing is a highly regulated
process that can be modulated by various behavioral and physiological factors such as …

[HTML][HTML] Cluster Headache and Hypoxia: Breathing New Life into an Old Theory, with Novel Implications

JM Borkum - Neurology International, 2024 - mdpi.com
Cluster headache is a severe, poorly understood disorder for which there are as yet virtually
no rationally derived treatments. Here, Lee Kudrow's 1983 theory, that cluster headache is …

Environmental Light Controls the Daily Organization of Breathing by Activating Brn3b-expressing Intrinsically Photosensitive Retinal Ganglion Cells in Mice

AA Jones, AR Spears, DM Arble - Journal of Biological …, 2024 - journals.sagepub.com
Rhythmic, daily fluctuations in minute ventilation are controlled by the endogenous circadian
clock located in the suprachiasmatic nucleus (SCN). While light serves as a potent …

[HTML][HTML] The MC4R agonist, setmelanotide, is associated with an improvement in hypercapnic chemosensitivity and weight loss in male mice

A Rivera, SN Framnes-DeBoer, DM Arble - Respiratory Physiology & …, 2025 - Elsevier
Obesity increases the risk of respiratory diseases that reduce respiratory chemosensitivity,
such as Obesity Hypoventilation Syndrome and sleep apnea. Recent evidence suggests …

Loss of endogenous circadian clock function in mice alters respiratory cycle timing in a time of day-and sex-specific manner

AA Jones, DM Arble - Respiratory Physiology & Neurobiology, 2025 - Elsevier
Resting breathing and ventilatory chemoreflexes are regulated in a 24-hr manner by the
endogenous circadian clock. However, it is unclear how circadian biology influences …