Fungal BGCs for production of secondary metabolites: main types, central roles in strain improvement, and regulation according to the piano principle

AA Zhgun - International Journal of Molecular Sciences, 2023 - mdpi.com
Filamentous fungi are one of the most important producers of secondary metabolites. Some
of them can have a toxic effect on the human body, leading to diseases. On the other hand …

Update on Mycochemical Profile and Selected Biological Activities of Genus Schizophyllum Fr. 1815

J Mišković, M Rašeta, N Krsmanović… - Microbiology …, 2023 - mdpi.com
The aim of this systematic review was to investigate new research on the antioxidant, anti-
acetylcholine, antimicrobial, and antitumor activity of genus Schizophyllum, as well as to …

Horizontal transfer and evolution of the biosynthetic gene cluster for benzoxazinoids in plants

D Wu, B Jiang, CY Ye, MP Timko, L Fan - Plant Communications, 2022 - cell.com
Benzoxazinoids are a class of protective and allelopathic plant secondary metabolites that
have been identified in multiple grass species and are encoded by the Bx biosynthetic gene …

Production of helvolic acid in Metarhizium contributes to fungal infection of insects by bacteriostatic inhibition of the host cuticular microbiomes

Y Sun, S Hong, H Chen, Y Yin, C Wang - Microbiology Spectrum, 2022 - Am Soc Microbiol
The nortriterpenoid helvolic acid (HA) has potent antibiotic activities and can be produced by
different fungi, yet HA function remains elusive. Here, we report the chemical biology of HA …

Old fusidane-type antibiotics for new challenges: Chemistry and biology

T Chuan, W Ke, X Zhang, LI Gang… - Chinese Journal of …, 2022 - Elsevier
The spread of antibiotic-resistant bacteria and exhausted drug leads render some infections
untreatable now and in the future. To deal with these “new challenges”, scientists tend to re …

Highlight: Virtual Issue on Host–Pathogen Interactions and Antimicrobial Drug Resistance

C McGrath - 2022 - academic.oup.com
A 2022 Virtual Issue from Genome Biology and Evolution (GBE) highlights recent articles on
the evolutionary dynamics of host–pathogen interactions and antimicrobial drug resistance …

Horizontal Transfer and Evolution of the Biosynthetic Gene Cluster for Benzoxazinoid

D Wu, B Jiang, CY Ye, MP Timko, L Fan - bioRxiv, 2021 - biorxiv.org
Benzoxazinoids are a class of protective and allelopathic plant secondary metabolites, first
identified in maize (Zea mays) and subsequently shown to be encoded by a biosynthetic …

[PDF][PDF] VERICA PETROVIĆ OLIVERA BATIĆ MUJANOVIĆ KOSANA STANETIĆ SUZANA SAVIĆ

Z JATIĆ - mednet-edu.net
Pandemija izazvana SARS CoV 2 virusom dovela je do mnogobrojnih promjena u
porodičnom i poslovnom životu ljudi širom svijeta. Predhodni period od dvije godine doveo …