Myelin oligodendrocyte glycoprotein (MOG), a member of the immunoglobulin (Ig)
superfamily, is a myelin protein solely expressed at the outermost surface of myelin sheaths …

The immune system plays a central role in the defense against environmental threats–such
as infection with viruses, parasites or bacteria–but can also be a cause of disease, such as …

In this unit, we describe in detail the most common methods used to break immunological
tolerance for central myelin antigens and induce experimental autoimmune …

Objective To determine whether animals with Japanese macaque encephalomyelitis (JME),
a spontaneous demyelinating disease similar to multiple sclerosis (MS), harbor myelin …

Background: Experimental autoimmune encephalomyelitis (EAE) induced by self-myelin
antigen is a widely used in multiple sclerosis (MS) model for preclinical studies of new …

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system,
characterized as an inflammatory demyelinating disease. Given the need for improvements …

In Rahmen dieser wissenschaftlichen Arbeit wurde der Nutzen von USPION als KM in der
MRTBildgebung für die Darstellung und Quantifizierung von Entzündungsaktivität in einem …

Infectious agents that induce cross-reactive myocarditic T cell responses may cause
autoimmune inflammation of the heart, dilated cardiomyopathy (DCM), and heart failure. The …

Figure 1. Booster immunizations with IgV-MOG in IFA caused a chronic course of atypical
EAE. Seven Lewis rats were immunized with a mixture of 25 μg of GP69-88 and 50 μg of rat …