Collagen is the main source of extracellular support for multicellular animals. The
mechanical strength of collagen fibrils depends on a highly regulated mechanism of …

Although musculoskeletal diseases such as osteoporosis are diagnosed and treatment
outcome is evaluated based mainly on routine clinical outcomes of bone mineral density …

Collagen fiber structure and organization have been found to vary in different tendon types.
Differences have been reported in the FT-IR spectra of the amide I band of collagen …

Introduction Enzymatic and glycation-induced nonenzymatic cross-links play important roles
in the expression of bone strength. The cross-link pattern is affected by tissue maturation …

Fourier-transform infrared microspectroscopy (FTIRM) allows analysis of mineral content,
mineral crystal maturity and mineral composition at~ 10-μ spatial resolution. Previous FTIRM …

Infrared spectroscopy, microspectroscopy, and microspectroscopic imaging have been used
to probe the composition and physicochemical status of mineral and matrix of bone in …

Bone quality is a complex set of intricated and interdependent factors that influence bone
strength. A number of methods have emerged to measure bone quality, taking into account …

Bone mineral composition, crystallinity, and bone mineral content of osteoporotic patients
are different from those of normal subjects. We review the evidence that these mineralization …

In the present study a rat animal model of lathyrism was employed to decipher whether
anatomically confined alterations in collagen cross-links are sufficient to influence the …

About this series The series Topics in Current Chemistry presents critical reviews of the
present and future trends in modern chemical research. The scope of coverage includes all …