Engineering precision nanoparticles for drug delivery

MJ Mitchell, MM Billingsley, RM Haley… - Nature reviews drug …, 2021 - nature.com
In recent years, the development of nanoparticles has expanded into a broad range of
clinical applications. Nanoparticles have been developed to overcome the limitations of free …

Engineering nano-drug biointerface to overcome biological barriers toward precision drug delivery

S Waheed, Z Li, F Zhang, A Chiarini, U Armato… - Journal of …, 2022 - Springer
The rapid advancement of nanomedicine and nanoparticle (NP) materials presents novel
solutions potentially capable of revolutionizing health care by improving efficacy …

[HTML][HTML] Multiple nano-drug delivery systems for intervertebral disc degeneration: Current status and future perspectives

W Liu, Z Ma, Y Wang, J Yang - Bioactive Materials, 2023 - Elsevier
Low back pain (LBP) is a common disease that imposes a huge social and economic
burden on people. Intervertebral disc (IVD) degeneration (IVDD) is often considered to be …

Liposomes for drug delivery: review of vesicular composition, factors affecting drug release and drug loading in liposomes

S Pande - Artificial Cells, Nanomedicine, and Biotechnology, 2023 - Taylor & Francis
Liposomes are considered among the most versatile and advanced nanoparticle delivery
systems used to target drugs to specific cells and tissues. Structurally, liposomes are sphere …

Nanoparticles in the diagnosis and treatment of vascular aging and related diseases

H Xu, S Li, YS Liu - Signal Transduction and Targeted Therapy, 2022 - nature.com
Aging-induced alternations of vasculature structures, phenotypes, and functions are key in
the occurrence and development of vascular aging-related diseases. Multiple molecular and …

Engineering nanosystems to overcome barriers to cancer diagnosis and treatment

SO Alhaj-Suliman, EI Wafa, AK Salem - Advanced drug delivery reviews, 2022 - Elsevier
Over the past two decades, multidisciplinary investigations into the development of
nanoparticles for medical applications have continually increased. However, nanoparticles …

Current advances in non‐viral gene delivery systems: Liposomes versus extracellular vesicles

Z Belhadj, Y Qie, RP Carney, Y Li, G Nie - BMEMat, 2023 - Wiley Online Library
In the past decade, nucleic acid‐based drugs have emerged as an extremely promising
approach for silencing specific disease‐related genes and targeting undruggable ones …

HOTAIR‐loaded mesenchymal stem/stromal cell extracellular vesicles enhance angiogenesis and wound healing

LJ Born, KH Chang, P Shoureshi, F Lay… - Advanced …, 2022 - Wiley Online Library
Chronic wounds remain a substantial source of morbidity worldwide. An emergent approach
that may be well‐suited to induce the complex, multicellular processes such as …

Nanotherapeutic treatment of the invasive glioblastoma tumor microenvironment

N Pandey, P Anastasiadis, CP Carney… - Advanced drug delivery …, 2022 - Elsevier
Glioblastoma (GBM) is the most common malignant adult brain cancer with no curative
treatment strategy. A significant hurdle in GBM treatment is effective therapeutic delivery to …

Microfluidic manufacture of lipid-based nanomedicines

K Osouli-Bostanabad, S Puliga, DR Serrano, A Bucchi… - Pharmaceutics, 2022 - mdpi.com
Nanoparticulate technologies have revolutionized drug delivery allowing for passive and
active targeting, altered biodistribution, controlled drug release (temporospatial or triggered) …