Peripheral nerves are particularly vulnerable to injuries and are involved in numerous
pathologies for which specific treatments are lacking. This review summarizes the …

In recent decades, artificial nerve scaffolds have become a promising substitute for
peripheral nerve repair. Considerable efforts have been devoted to improving the …

Intervertebral disc degeneration (IVDD) has been the major contributor to chronic lower back
pain (LBP). Abnormal apoptosis, senescence, and pyroptosis of IVD cells, extracellular …

Adipose tissue is a rich source of cells with emerging promise for tissue engineering and
regenerative medicine. The stromal vascular fraction (SVF), in particular, is an eclectic …

Bridging critical‐sized defects in peripheral nerves to achieve functional recovery is a
challenge for orthopedic and hand surgeons. Inadequate regeneration of peripheral nerve …

Stroke represents a severe medical condition that causes stroke survivors to suffer from long-
term and even lifelong disability. Over the past several decades, a vast majority of stroke …

Injured peripheral neurons successfully activate a proregenerative transcriptional program
to enable axon regeneration and functional recovery. How transcriptional regulators …

Controlled delivery of multiple therapeutic agents can be considered an effective approach
in nerve injury due to its multifunction. In this study, recombinant human vascular endothelial …

Peripheral nerve injury (PNI) is a common disease in clinic, and the regeneration process of
peripheral nerve tissue is slow, and patients with PNI often suffer from the loss of nerve …

The intrinsic ability of peripheral nerves to regenerate after injury is extremely limited,
especially in case of severe injury. This often leads to poor motor function and permanent …