Computational modelling of the lungs is an active field of study that integrates computational
advances with lung biophysics, biomechanics, physiology and medical imaging to promote …

Pulmonary diseases, driven by pollution, industrial farming, vaping, and the infamous
COVID-19 pandemic, lead morbidity and mortality rates worldwide. Computational …

Pulmonary air leaks are amongst the most common complications in lung surgery. Lung
sealants are applied to the organ surface and need to synchronously stretch with the …

Background Common respiratory illnesses, such as emphysema and chronic obstructive
pulmonary disease, are characterized by connective tissue damage and remodeling. Two …

Rationale: There is continued debate regarding the equivalency of positive-pressure
ventilation (PPV) and negative-pressure ventilation (NPV). Resolving this question is …

Tissue remodeling in pulmonary disease irreversibly alters lung functionality and impacts
quality of life. Mechanical ventilation is amongst the few pulmonary interventions to aid …

Respiratory pathologies alter the structure of the lung and impact its mechanics. Mice are
widely used in the study of lung pathologies, but there is a lack of fundamental mechanical …

Distal airways commonly obstruct in lung disease and despite their importance, their
mechanical properties are vastly underexplored. The lack of bronchial experiments restricts …

COVID-19 infection caused by SARS-CoV-2 is considered catastrophic because it affects
multiple organs, particularly those of the respiratory tract. Although the consequences of this …

Pulmonary diseases alter lung mechanical properties, can cause loss of function, and
necessitate use of mechanical ventilation, which can be detrimental. Investigations of lung …