Background Natural polyphenols provide numerous human-health promoting benefits,
including gut microbiota regulation, microbial composition changes, and improvement of …

The sirtuin system consists of seven highly conserved regulatory enzymes responsible for
metabolism, antioxidant protection, and cell cycle regulation. The great interest in sirtuins is …

Background: Resveratrol is a polyphenol chemical that naturally occurs in many plant-based
dietary products, most notably, red wine. Discovered in 1939, widespread interest in the …

Antioxidants are a collection of substances that may prevent or delay the oxidation of cellular
components. The antioxidant defense system includes both endogenously produced …

This study evaluated the stability of a novel nutraceutical formulation composed of the
probiotic Limosilactobacillus fermentum 296, quercetin (QUE), and resveratrol (RES)(LFQR) …

Abstract SIRT1 (Sirtuin 1) is a NAD+-dependent deacetylase that functions through
nucleoplasmic transfer and is present in nearly all mammalian tissues. SIRT1 is believed to …

Plant-Derived Extracellular Vesicles extracellular vesicles (PDEVs) from organic agriculture
(without the use of pesticides and microbicides) contain high levels of antioxidants. Organic …

Background and purpose: Pedestrians are the most vulnerable people in the traffic system,
and every year, thousands of pedestrians are injured or killed due to traffic accidents. The …

Purpose Caloric restriction (CR), the permanent or periodic reduction of caloric intake, is a
dietary strategy that promotes longevity and healthspan, yielding multiple beneficial effects …

The worldwide trend toward an aging population has resulted in a higher incidence of
chronic conditions, such as osteoporosis. Osteoporosis, a prevalent skeletal disorder …