Angiogenesis is an essential process in normal development and in adult physiology, but
can be disrupted in numerous diseases. The concept of targeting angiogenesis for treating …

Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining
health and homeostasis. Although white adipose tissue and brown adipose tissue are …

Glucose uptake is essential for cancer glycolysis and is involved in non-shivering
thermogenesis of adipose tissues,,,,–. Most cancers use glycolysis to harness energy for …

The worldwide incidence of obesity and its sequelae, such as type 2 diabetes mellitus, have
reached pandemic levels. Central to the development of these metabolic disorders is …

Brown adipose tissue (BAT) dissipates energy, and promotes cardiometabolic health. Loss
of BAT during obesity and ageing is a principal hurdle for BAT-centred obesity therapies, but …

Angiogenesis has always been the topic of major scientific interest in the field of malignant
tumors. Nowadays, targeting angiogenesis has achieved success in various carcinomas by …

Our understanding of the role of the vascular endothelium has evolved over the past 2
decades, with the recognition that it is a dynamically regulated organ and that it plays a …

Platelet-derived growth factors (PDGF) promotes cell proliferation, survival and migration,
primarily of cells of mesenchymal origin. Dysfunction of PDGF signaling has been observed …

Adipose tissue is an endocrine organ and a crucial regulator of energy storage and systemic
metabolic homeostasis. Additionally, adipose tissue is a pivotal regulator of cardiovascular …

Intermittent fasting (IF), a periodic energy restriction, has been shown to provide health
benefits equivalent to prolonged fasting or caloric restriction. However, our understanding of …