Glycosylation is essential to brain development and function, but prior studies have often been limited to a single analytical technique and excluded region-and sex-specific analyses …
J Lee, S Ha, M Kim, SW Kim, J Yun… - Proceedings of the …, 2020 - National Acad Sciences
Mammalian brain glycome remains a relatively poorly understood area compared to other large-scale “omics” studies, such as genomics and transcriptomics due to the inherent …
DJ Harvey - Mass Spectrometry Reviews, 2021 - Wiley Online Library
This review is the ninth update of the original article published in 1999 on the application of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …
H Kang, A Han, A Zhang, H Jeong, W Koh… - Nature …, 2024 - nature.com
Impaired ion channels regulating Golgi pH lead to structural alterations in the Golgi apparatus, such as fragmentation, which is found, along with cognitive impairment, in …
At mammalian neuronal synapses, synaptic vesicle (SV) glycoproteins are essential for robust neurotransmission. Asparagine (N)-linked glycosylation is required for delivery of the …
NS Sim, Y Seo, JS Lim, WK Kim, H Son… - Neurology …, 2018 - AAN Enterprises
Objective To identify whether somatic mutations in SLC35A2 alter N-glycan structures in human brain tissues and cause nonlesional focal epilepsy (NLFE) or mild malformation of …
J Samal, TV Palomino, J Chen, DC Muddiman… - Analytical …, 2023 - ACS Publications
N-linked glycosylation represents a structurally diverse, complex, co-and posttranslational protein modification that bridges metabolism and cellular signaling. Consequently, aberrant …
M Otaki, N Hirane, Y Natsume-Kitatani… - Scientific reports, 2022 - nature.com
This study presents “mouse tissue glycome atlas” representing the profiles of major N- glycans of mouse glycoproteins that may define their essential functions in the surface …
E Lattová, J Skřičková, J Hausnerová, L Frola, L Křen… - Modern Pathology, 2020 - Elsevier
Lung adenocarcinoma (LAC) is the most common form of lung cancer that increases in non- smokers at younger age. Altered protein glycosylation is one of the hallmarks of malignancy …