Environmental and genetic risk factors associated with venous thromboembolism
M Crous-Bou, LB Harrington… - Seminars in thrombosis …, 2016 - thieme-connect.com
Venous thromboembolism (VTE) includes deep vein thrombosis and pulmonary embolism,
and a combination of environmental and genetic risk factors contributes to VTE risk. Within …
and a combination of environmental and genetic risk factors contributes to VTE risk. Within …
Polygenic risk scores: An overview from bench to bedside for personalised medicine
B Cross, R Turner, M Pirmohamed - Frontiers in Genetics, 2022 - frontiersin.org
Since the first polygenic risk score (PRS) in 2007, research in this area has progressed
significantly. The increasing number of SNPs that have been identified by large scale GWAS …
significantly. The increasing number of SNPs that have been identified by large scale GWAS …
A clinical-genetic risk score for predicting cancer-associated venous thromboembolism: a development and validation study involving two independent prospective …
PURPOSE Venous thromboembolism (VTE) is a leading cause of death among patients with
cancer. The Khorana score was developed for assessing the risk of VTE in outpatients with …
cancer. The Khorana score was developed for assessing the risk of VTE in outpatients with …
Multivariable clinical-genetic risk model for predicting venous thromboembolic events in patients with cancer
AJ Munoz Martin, I Ortega, C Font, V Pachón… - British journal of …, 2018 - nature.com
Background Venous thromboembolism (VTE) is a leading cause of death among patients
with cancer. Outpatients with cancer should be periodically assessed for VTE risk, for which …
with cancer. Outpatients with cancer should be periodically assessed for VTE risk, for which …
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods
Genome biology, 2024 - Springer
Abstract Background The Critical Assessment of Genome Interpretation (CAGI) aims to
advance the state-of-the-art for computational prediction of genetic variant impact …
advance the state-of-the-art for computational prediction of genetic variant impact …
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods
S Jain, C Bakolitsa, SE Brenner, P Radivojac… - Genome …, 2024 - lirias.kuleuven.be
Abstract Background: The Critical Assessment of Genome Interpretation (CAGI) aims to
advance the state-of-the-art for computational prediction of genetic variant impact …
advance the state-of-the-art for computational prediction of genetic variant impact …
Genetic risk factors in venous thromboembolism
C Hotoleanu - Thrombosis and Embolism: from Research to Clinical …, 2017 - Springer
Genetic risk factors predispose to thrombophilia and play the most important etiopathogenic
role in venous thromboembolism (VTE) in people younger than 50 years old. At least one …
role in venous thromboembolism (VTE) in people younger than 50 years old. At least one …
[HTML][HTML] The UCLA ATLAS Community Health Initiative: promoting precision health research in a diverse biobank
Summary The UCLA ATLAS Community Health Initiative (ATLAS) has an initial target to
recruit 150,000 participants from across the UCLA Health system with the goal of creating a …
recruit 150,000 participants from across the UCLA Health system with the goal of creating a …
Prediction of primary venous thromboembolism based on clinical and genetic factors within the UK Biobank
DA Kolin, S Kulm, O Elemento - Scientific reports, 2021 - nature.com
Both clinical and genetic factors drive the risk of venous thromboembolism. However,
whether clinically recorded risk factors and genetic variants can be combined into a clinically …
whether clinically recorded risk factors and genetic variants can be combined into a clinically …
[HTML][HTML] Predicting venous thrombosis in women using a combination of genetic markers and clinical risk factors
M Bruzelius, M Bottai, M Sabater‐Lleal… - Journal of Thrombosis …, 2015 - Elsevier
Background Family history of venous thromboembolism (VTE) has been suggested to be
more useful in risk assessment than thrombophilia testing. Objectives We investigated …
more useful in risk assessment than thrombophilia testing. Objectives We investigated …