A Greener Synthetic Approach to Tetrazoles via Multicomponent Reactions

D Ray - Current Organocatalysis, 2023 - ingentaconnect.com
The synthesis of heterocyclic compounds has drawn considerable attention in the scientific
community due to their existence in the majority of medicinal & pharmaceutically important …

Mechanisms, copper catalysts, and ligands involved in the synthesis of 1, 2, 3-triazoles using click chemistry

E Leyva, I Rubén Rodríguez-Gutiérrez… - Current Organic …, 2022 - ingentaconnect.com
In the last two decades, click chemistry has become a modular synthetic procedure to
assemble new molecular structures. It is a powerful methodology that relies on the …

[PDF][PDF] Tackling the SARS-CoV-2 main protease using hybrid derivatives of 1, 5-disubstituted tetrazole-1, 2, 3-triazoles: an in silico assay

CJ Cortés-García, L Chacón-García… - PeerJ Physical …, 2020 - peerj.com
In regard to the actual public health global emergency and, based on the state of the art
about the ways to inhibit the SARS-CoV-2 treating the COVID19, a family of 1, 5 …

A one-pot six-component reaction for the synthesis of 1, 5-disubstituted tetrazol-1, 2, 3-triazole hybrids and their cytotoxic activity against the MCF-7 Cell Line

CM Aguilar-Morales, JG Araujo-Huitrado… - Molecules, 2021 - mdpi.com
A high-order multicomponent reaction involving a six-component reaction to obtain the novel
linked 1, 5-disubstituted tetrazole-1, 2, 3-triazole hybrids in low to moderate yield is …

A one-pot five component reaction for the synthesis of tetrazol-benzofuran hybrids and their inhibitory activity against Mucor lusitanicus

CM Aguilar-Morales, V Alejandre-Castañeda… - Organic & …, 2024 - pubs.rsc.org
A synthetic strategy for obtaining a new series of 1, 5-disubstituted tetrazole-benzofuran
hybrid systems via a one-pot five-component reaction is described. This process involves a …

Late‐stage functionalization of Vouacapane derivatives from Caesalpinia platyloba by a Groebke−Blackburn−Bienaymé reaction

G Servín‐García, L Chacón‐García… - Journal of …, 2023 - Wiley Online Library
An almost underexplored field within the natural products area is the synthesis of pseudo‐
natural product libraries by employing isocyanide‐based multicomponent reactions as …

Synthesis of novel fluoro phenyl triazoles via click chemistry with or without microwave irradiation and their evaluation as anti-proliferative agents in SiHa cells

J Aguilar, E Leyva, SE Loredo-Carrillo… - Current Organic …, 2024 - ingentaconnect.com
Aims: Perform the synthesis of novel fluoro phenyl triazoles via click chemistry with or
without microwave irradiation and their evaluation as anti-proliferative agents in SiHa cells …

Synthesis of 1,5‐Disubstituted Tetrazole−Indolizine Bis‐Heterocycles and Their Copper (II) Recognizing Properties

I Niño‐Pantoja, A Gallardo‐Alfonzo… - European Journal of …, 2022 - Wiley Online Library
A novel bis‐heterocyclic system encompassing the 1, 2‐dihydro‐3H‐pyrrolo [3, 4‐b]
indolizin‐3‐one and 1, 5‐disubstituted tetrazole moieties was designed, synthesized, and …

Synthesis of novel hybrid 1,5-disusbtituted 1H-tetrazol-5yl 4,5-dihydro [1,2,3]triazolo[1,5-a]pyrazin-6-ones via high-order MCR-SN2/intramolecular [3 + 2] …

CM Aguilar-Morales, G Servín-García… - Synthetic …, 2023 - Taylor & Francis
A facile and rapid synthesis of a family of new hybrid system 1, 5-disusbtituted 1 H-tetrazol-
5yl 4, 5-dihydro [1, 2, 3] triazolo [1, 5-a] pyrazin-6-ones in moderate yields is described …

Synthesis of Benzofuran‐Based Hybrid Molecules: Molecular Docking and Antibacterial Activity Against Pseudomonas aeruginosa

CJ Cortés‐García, AI Mercado‐Madrigal… - Journal of …, 2024 - Wiley Online Library
ABSTRACT A rapid and efficient protocol for synthesizing two series of benzofuran‐based
hybrid polyheterocycles is presented: benzofuran‐isatin and benzofuran N‐acylhydrazones …