Central sensitization (CS) is defined as an increased nociceptive responsiveness due to
sensitization of neurons in the central nervous system, usually the result of prolonged …

Nociplastic pain is a recently distinguished type of pain, distinct from neuropathic and
nociceptive pain, and is well described in the literature. It is often mistaken for central …

Chronic pain causes disability and loss of health worldwide. Yet, a mechanistic explanation
for it is still missing. Frequently, neural phenomena, and among them, Central Sensitization …

Background Central sensitization (CS) is becoming increasingly recognized as a significant
factor in many chronic pain conditions, including knee osteoarthritis (KOA) and chronic low …

Objective Posttraumatic stress disorder (PTSD) and traumatic life events are often coupled to
chronic pain, possibly linked by central sensitization. We wanted to assess the prevalence of …

Background Early evidence suggests human assumed central sensitization (HACS) is
present in some people with acute low back pain (LBP). Factors influencing individual …

Objectives: We aimed to explore the possible effects of musculoskeletal diagnosis and test
site on QST interrater and test–retest reliability. Methods: The study included participants …

Background and objectives Chronic low back pain (CLBP) is a leading cause of disability.
The management guidelines for the management of CLBP often recommend optimizing …

Purpose Systematic reviews evaluating and comparing the measurement properties of
outcome measurement instruments (OMIs) play an important role in OMI selection. Earlier …

Central sensitization (CS) involves an amplification of neural processing within the central
nervous system that can result in widespread pain patterns and hypersensitivity to stimuli …