Normal and dysregulated crosstalk between iron metabolism and erythropoiesis

Y Ginzburg, X An, S Rivella, A Goldfarb - Elife, 2023 - elifesciences.org
Erythroblasts possess unique characteristics as they undergo differentiation from
hematopoietic stem cells. During terminal erythropoiesis, these cells incorporate large …

Regulation of heme synthesis by mitochondrial homeostasis proteins

YY Yien, M Perfetto - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Heme plays a central role in diverse, life-essential processes that range from ubiquitous,
housekeeping pathways such as respiration, to highly cell-specific ones such as oxygen …

Red blood cell morphologic abnormalities in patients hospitalized for COVID-19

G Marchi, C Bozzini, L Bertolone, F Dima… - Frontiers in …, 2022 - frontiersin.org
Peripheral blood smear is a simple laboratory tool, which remains of invaluable help for
diagnosing primary and secondary abnormalities of blood cells despite advances in …

Quercetin inhibits the progression of endometrial HEC-1-A cells by regulating ferroptosis—a preliminary study

X Li, Q Zhu, M Ma, H Guo - European Journal of Medical Research, 2022 - Springer
Background Endometrial carcinoma (EC) is one of the most common female reproductive
system tumors, which seriously threatens women's health. This preliminary study aimed to …

The decline in cellular iron is crucial for differentiation in keratinocytes

J Abe, Y Aono, Y Hirai - Metallomics, 2024 - academic.oup.com
Iron is a vital metal for most biological functions in tissues, and its concentration is
exquisitely regulated at the cellular level. During the process of differentiation, keratinocytes …

Ferritin-mediated mitochondrial iron homeostasis is essential for the survival of hematopoietic stem cells and leukemic stem cells

W Yi, J Zhang, Y Huang, Q Zhan, M Zou, X Cheng… - Leukemia, 2024 - nature.com
Iron metabolism plays a crucial role in cell viability, but its relationship with adult stem cells
and cancer stem cells is not fully understood. The ferritin complex, responsible for …

[HTML][HTML] Analysis of the stereoselective fate and toxicity of penflufen in the water-sediment system for risk reduction

T Liu, S Yan, W Sun, X You, L Zheng, X Wang - Environment International, 2024 - Elsevier
Chiral succinate dehydrogenase inhibitor (SDHI) fungicides are widely used in agricultural
production, but there is insufficient research on their environmental risk in water–sediment …

DMT1 Maintains Iron Homeostasis to Regulate Mitochondrial Function in Porcine Oocytes

JX Zhang, MF Lan, JZ Shang, XL Lai… - Journal of Cellular …, 2024 - Wiley Online Library
Iron plays critical roles in many cellular functions, including energy production, metabolism,
and cell proliferation. However, the role of iron in maintaining oocyte quality remains …

TNFα‐induced abnormal activation of TNFR/NF‐κB/FTH1 in endometrium is involved in the pathogenesis of early spontaneous abortion

Y Wen, M Cheng, L Qin, W Xu - Journal of cellular and …, 2022 - Wiley Online Library
Early spontaneous abortion (ESA) is one of the most common complications during
pregnancy and the inflammation condition in uterine environment such as long‐term …

IL-1/MyD88–Dependent G-CSF and IL-6 Secretion Mediates Postburn Anemia

JG Noel, SW Ramser, L Pitstick… - The Journal of …, 2023 - journals.aai.org
The anemia of critical illness (ACI) is a nearly universal pathophysiological consequence of
burn injury and a primary reason burn patients require massive quantities of transfused …