[HTML][HTML] HIV-1 Reverse Transcriptase/Integrase dual inhibitors: A review of recent advances and structure-activity relationship studies

M Mahboubi-Rabbani, M Abbasi… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
The significant threat to humanity is HIV infection, and it is uncertain whether a definitive
treatment or a safe HIV vaccine is. HIV-1 is continually evolving and resistant to commonly …

Design and synthesis of novel quinazolinone-pyrazole derivatives as potential α-glucosidase inhibitors: Structure-activity relationship, molecular modeling and kinetic …

F Azimi, H Azizian, M Najafi, F Hassanzadeh… - Bioorganic …, 2021 - Elsevier
In this study, a new series of quinazolinone-pyrazole hybrids were designed, synthesized
and screened for their α-glucosidase inhibitory activity. The results of the in vitro screening …

A green synthesis of pyrimido [4, 5-b] quinolines and pyrido [2, 3-d] pyrimidines via a mechanochemical approach

HK Singh, A Kamal, SK Maury, AK Kushwaha… - Organic & …, 2023 - pubs.rsc.org
A cost-effective and competent approach has been established for the synthesis of pyrimido
[4, 5-b] quinolines and pyrido [2, 3-d] pyrimidines via a multicomponent reaction of 1, 3 …

Antimicrobial activity of halogen-and chalcogen-functionalized thiazoloquinazolines

D Kut, M Kut… - Letters in Drug …, 2024 - benthamdirect.com
The investigation is devoted to the assessment of the potential antimicrobial use of new
chalcogen-functionalized thiazolo [2, 3-b] quinazolin-5-ones, halides and trihalides of …

Design, synthesis, molecular modeling and anti-HIV assay of novel quinazolinone incorporated coumarin derivatives

M Safakish, Z Hajimahdi, MR Aghasadeghi… - Current HIV …, 2020 - ingentaconnect.com
Background: The emergence of drug-resistant viral strains has created the need for the
development of novel anti-HIV agents with a diverse structure that targets key enzymes in …

Role of computational modelling in drug discovery for HIV

A Gomatam, A Khan, K Raikuvar, M D'costa… - Current Trends in …, 2023 - Springer
With over 36 million people currently living with HIV, HIV/AIDS continues to have devastating
effects on human health worldwide. Viral resistance to anti-HIV drugs remains a major cause …

Synthesis and characterization of Schiff bases derived from 3-aryl-2-formyl-4 (3H)-quinazolinone

MHA Soliman, SSSA El-Sakka, RM Kamel… - Frontiers in Scientific …, 2023 - journals.ekb.eg
Condensation of 3-aryl-4 (3H)-quinazolinone-2-carbaldehydes with different substituted
aniline under reflux conditions afforded a series of Schiff bases (imines) containing …

[HTML][HTML] Design, Synthesis, Molecular Modeling Study and Biological Evaluation of New N'-Arylidene-pyrido [2, 3-d] pyrimidine-5-carbohydrazide Derivatives as Anti …

E Ebrahimzadeh, SA Tabatabai… - Iranian Journal of …, 2019 - ncbi.nlm.nih.gov
Design, Synthesis, Molecular Modeling Study and Biological Evaluation of New N'-Arylidene-pyrido
[2,3-d]pyrimidine-5-carbohydrazide Derivatives as Anti-HIV-1 Agents - PMC Back to Top Skip …

[HTML][HTML] Design, Synthesis, molecular modeling studies and biological evaluation of N′-arylidene-6-(benzyloxy)-4-oxo-1, 4-dihydroquinoline-3-carbohydrazide …

SMIM Rabbani, R Vahabpour… - Iranian Journal of …, 2019 - ncbi.nlm.nih.gov
Design, Synthesis, Molecular Modeling Studies and Biological Evaluation of N′-Arylidene-6-(benzyloxy)-4-oxo-1,4-dihydroquinoline-3-carbohydrazide
Derivatives as Novel Anti-HCV Agents - PMC Back to Top Skip to main content NIH NLM …

Design, Synthesis and Docking studies of New Quinazolinone Derivatives as Anti-HIV-1 Agents: Quinazolinone Derivatives as Anti-HIV-1 Agents

T Zebardast, N Mostafavi, S Sharifi… - Iranian Journal of …, 2022 - vclass.sbmu.ac.ir
Design, Synthesis and Docking studies of New Quinazolinone Derivatives as Anti-HIV-1
Agents Page 1 Iranian Journal of Pharmaceutical Sciences 2022: 18 (1): 55-64 www.ijps.ir …