Acidosis is a well recognised consequence of myocardial ischaemia. In this brief article we
have reviewed the consequences of acidosis that might be arrhythmogenic. These include …

Analysis of the effects of changes in rate and rhythm upon electrical activity in the heart -
ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Search …

We studied the individual and combined effects of extracellular acidosis and increases in
extracellular potassium on action potential characteristics and conduction in order to gain a …

Background—The hyperpolarization-activated inward current (If) was found to be
overexpressed in hypertrophied rat ventricular myocytes, indicating that If might favor …

We sought to determine whether extracellular Ca 2+(Ca e 2+) and K+(K e+) play essential
roles in the normal functioning of cardiac K+ channels. Reports by others have shown that …

1. Passive electrical properties of sheep cardiac Purkinje fibres were assessed by
performing linear cable analysis. In a separate set of experiments pHi was monitored using …

Myocardial ischemia leads to conduction slowing, cell-to-cell uncoupling, and arrhythmias.
We previously demonstrated that varying perfusate sodium (Na+) and calcium (Ca2+) …

We have investigated the effects of H ions on (L-type) Ca channel current in isolated
ventricular cells. We find that the current amplitude is enhanced in solutions that are alkaline …

Effects of extracellular pH on the sodium current (I Na) of single rat ventricular cells were
examined under conditions of voltage clamp and internal perfusion. In this way, pH i was …

Delayed rectifier outward K+ current (IK) in guinea pig ventricular myocytes represents the
sum of two currents: a slowly activating delayed rectifier K+ current (IK. s) and a relatively …