Mitochondria play important roles in maintaining cellular homeostasis and skeletal muscle
health, and damage to mitochondria can lead to a series of pathophysiological changes …

Malnutrition is a common comorbidity in patients with cirrhosis. Its prognostic value is
indisputable as it greatly affects the evolution of liver diseases. It has a major impact on both …

This is the first American Association for the Study of Liver Diseases (AASLD) practice
guidance on the management of malnutrition, frailty, and sarcopenia in patients with …

Background Diagnostic criteria for sarcopenia have not been established in Chinese. This
study established criteria based on the L3‐skeletal muscle index (L3‐SMI) and assessed its …

The prevalence of osteoporosis and sarcopenia is significantly higher in patients with liver
disease than in those without liver disease and osteoporosis and sarcopenia negatively …

Abstract Changes in body composition are associated with poor outcomes in cancer patients
including hepatocellular carcinoma (HCC). Sarcopenia, defined as the loss of skeletal …

Liver cirrhosis is frequently accompanied by disease-related malnutrition (DRM) and
sarcopenia, defined as loss of skeletal muscle mass and function. DRM and sarcopenia …

Malnutrition is a common condition encountered in patients with inflammatory bowel disease
(IBD) and is often associated with sarcopenia (the reduction of muscle mass and strength) …

Insulin resistance (IR) is defined as a lower-than-expected response to insulin action from
target tissues, leading to the development of type 2 diabetes through the impairment of both …

Myostatin is a member of the transforming growth factor (TGF)-β superfamily. It is expressed
by animal and human skeletal muscle cells where it limits muscle growth and promotes …