Abnormalities in the mitogen-activated protein kinase (MAPK) signaling pathway are a key
contributor to the carcinogenesis process and have therefore been implicated in several …

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and highly fatal
neurodegenerative disease. Although the pathogenesis of ALS remains unclear, increasing …

Inflammation is a natural host defense mechanism that protects the body from pathogenic
microorganisms. A growing body of research suggests that inflammation is a key factor in …

Polyphenols are a class of secondary metabolic products found in plants that have been
extensively studied for how well they regulate biological processes, such as the proliferation …

Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of central
nervous system (CNS). Aging is the most significant risk factor for the progression of MS …

Aging is associated with the occurrence of diverse degenerative changes in various tissues
and organs and with an increased incidence of neurological disorders, especially …

Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) and Lou
Gehrig's disease, is characterized by a loss of the lower motor neurons in the spinal cord …

Hydrogen sulfide (H 2 S) is an environmental contaminant to cause the airway damage. The
release of macrophage extracellular traps (METs) is the mechanism of immune protection to …

Current treatments for neurodegenerative diseases (ND) are symptomatic and do not affect
disease progression. Slowing this progression remains a crucial unmet need for patients …

Inflammation, although necessary to fight infections, becomes a threat when it exceeds the
capability of the immune system to control it. In addition, inflammation is a cause and/or …