Colorectal liver metastasis: molecular mechanism and interventional therapy

H Zhou, Z Liu, Y Wang, X Wen, EH Amador… - Signal transduction and …, 2022 - nature.com
Colorectal cancer (CRC) is one of the most frequently occurring malignancy tumors with a
high morbidity additionally, CRC patients may develop liver metastasis, which is the major …

miR‐146a‐5p: expression, regulation, and functions in cancer

JR Iacona, CS Lutz - Wiley Interdisciplinary Reviews: RNA, 2019 - Wiley Online Library
Cancer as we know it is actually an umbrella term for over 100 very unique malignancies in
various tissues throughout the human body. Each type, and even subtype of cancer, has …

MicroRNA-146a limits tumorigenic inflammation in colorectal cancer

LP Garo, AK Ajay, M Fujiwara, G Gabriely… - Nature …, 2021 - nature.com
Chronic inflammation can drive tumor development. Here, we have identified microRNA-
146a (miR-146a) as a major negative regulator of colonic inflammation and associated …

The regulation of protein translation and its implications for cancer

P Song, F Yang, H Jin, X Wang - Signal transduction and targeted …, 2021 - nature.com
In addition to the deregulation of gene transcriptions and post-translational protein
modifications, the aberrant translation from mRNAs to proteins plays an important role in the …

Drug resistance in colorectal cancer: An epigenetic overview

M Luo, X Yang, HN Chen, EC Nice, C Huang - Biochimica et Biophysica …, 2021 - Elsevier
Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. Despite
significant progress that has been made in therapies against CRC over the past decades …

MiRNA-146a—A Key Player in Immunity and Diseases

I Gilyazova, D Asadullina, E Kagirova, R Sikka… - International Journal of …, 2023 - mdpi.com
miRNA-146a, a single-stranded, non-coding RNA molecule, has emerged as a valuable
diagnostic and prognostic biomarker for numerous pathological conditions. Its primary …

Osteopontin as a regulator of colorectal cancer progression and its clinical applications

K Amilca-Seba, M Sabbah, AK Larsen, JA Denis - Cancers, 2021 - mdpi.com
Simple Summary The mortality of colorectal cancer is principally related to metastatic
disease at the time of diagnosis or to the growth of initially undetectable micro-metastasis …

Increased expression of long non-coding RNA SNHG16 correlates with tumor progression and poor prognosis in non-small cell lung cancer

W Han, X Du, M Liu, J Wang, L Sun, Y Li - International journal of biological …, 2019 - Elsevier
In this study, we report that lncRNA SNHG16 is upregulated in non-small cell lung cancer
(NSCLC) tissues, and correlates with tumor size, TNM stage and lymph node metastasis …

Colorectal cancer stem cells in the progression to liver metastasis

CA Gonzalez-Villarreal, AG Quiroz-Reyes… - Frontiers in …, 2020 - frontiersin.org
Colorectal carcinoma (CRC) is a leading cause of cancer mortality. Tumorigenesis is a
dynamic process wherein cancer stem cells (CSCs) and their microenvironment promote …

The potential therapeutic and prognostic impacts of the c‐MET/HGF signaling pathway in colorectal cancer

SM Parizadeh, R Jafarzadeh‐Esfehani… - IUBMB …, 2019 - Wiley Online Library
Colorectal cancer (CRC) is the third most common cancer and a common cause of cancer‐
related mortality globally. In spite of the improvements in the early diagnosis of CRC …