Ligands of CD6: roles in the pathogenesis and treatment of cancer
M Gurrea-Rubio, F Lin, MS Wicha… - Frontiers in …, 2025 - frontiersin.org
Cluster of Differentiation 6 (CD6), an established marker of T cells, has multiple and complex
functions in regulation of T cell activation and proliferation, and in adhesion of T cells to …
functions in regulation of T cell activation and proliferation, and in adhesion of T cells to …
CD6 regulates CD4 T follicular helper cell differentiation and humoral immunity during murine coronavirus infection
A Cardani-Boulton, F Lin, CC Bergmann - Journal of Virology, 2024 - journals.asm.org
During activation, the T cell transmembrane receptor CD6 becomes incorporated into the T
cell immunological synapse where it can exert both co-stimulatory and co-inhibitory …
cell immunological synapse where it can exert both co-stimulatory and co-inhibitory …
Histone methyltransferase DOT1L maintains identity and restricts cytotoxic potential of CD8 T cells
M Malik, WJ de Leeuw, MA Aslam… - bioRxiv, 2025 - biorxiv.org
The histone methyltransferase DOT1L is emerging as a central epigenetic regulator in
immune cells. Loss of DOT1L during development of CD8 T cells in vivo leads to gain of …
immune cells. Loss of DOT1L during development of CD8 T cells in vivo leads to gain of …