It is well established that the large array of functions that a tumour cell has to fulfil to settle as
a metastasis in a distant organ requires cooperative activities between the tumour and the …

Galectin-3 has been suspected of modulating cell to extracellular matrix interactions in a
novel fashion ever since it was first described. However, the rapid accumulation of research …

Many studies have shown the central importance of the co-receptors CD28, inducible
costimulatory molecule (ICOS) and cytotoxic T lymphocyte antigen 4 (CTLA4) in the …

Endogenous intestinal microflora and environmental factors, such as diet, play a central role
in immune homeostasis and reactivity. In addition, microflora and diet both influence body …

Rafts have been conceptualized as lateral heterogeneities in the organization of cholesterol
and sphingolipids, endowed with sorting and signaling functions. In this review we critically …

Cholesterol is a neutral lipid that accumulates in liquid‐ordered, detergent‐resistant
membrane domains called lipid rafts. Lipid rafts serve as membrane platforms for signal …

Les cavéoles ont été décrites pour la première fois il ya environ 50 ans. Pendant plusieurs
décennies, elles sont demeurées principalement intéressantes pour les biologistes …

Local surface charge density of lipid membranes influences membrane–protein interactions
leading to distinct functions in all living cells, and it is a vital parameter in understanding …

Signal peptide-CUB-EGF domain-containing protein 3 (SCUBE3) is a member of a small
family of multifunctional cell surface-anchored glycoproteins functioning as co-receptors for …

In eukaryotic cells the phospholipid phosphatidylserine (PS) is restricted to the inner plasma-
membrane leaflet. This lipid asymmetry, which is maintained by the concerted action of …