An exceptional safety profile has been shown in a large number of cell therapy clinical trials
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …

The essential physiological role of platelets in wound healing and tissue repair builds the
rationale for the use of human platelet derivatives in regenerative medicine. Abundant …

Mesenchymal stromal cells (MSCs) as a pharmaceutical for ailments characterized by
pathogenic autoimmune, alloimmune and inflammatory processes now cover the spectrum …

Compared with traditional 2D adherent cell culture, 3D spheroidal cell aggregates, or
spheroids, are regarded as more physiological, and this technique has been exploited in the …

Mesenchymal stromal cells (MSC) have gained immense attraction in regenerative
medicine, tissue engineering, and immunotherapy. This is based on their differentiation …

Mesenchymal stem/stromal cell (MSC) exist within their in vivo niches as part of
heterogeneous cell populations, exhibiting variable stemness potential and supportive …

Because of their well-recognized immunomodulatory properties, mesenchymal stromal cells
(MSCs) represent an attractive cell population for therapeutic purposes. In particular, there is …

Four decades of preclinical research demonstrating survival, functional integration, and
behavioral effects of transplanted stem cells in experimental stroke models have provided …

Around 40% of the population will suffer at some point in their life a disease involving tissue
loss or an inflammatory or autoimmune process that cannot be satisfactorily controlled with …

Undesired immune responses have drastically hampered outcomes after allogeneic organ
transplantation and cell therapy, and also lead to inflammatory diseases and autoimmunity …