[HTML][HTML] Exosomes and cancer-Diagnostic and prognostic biomarkers and therapeutic vehicle

X Wang, L Tian, J Lu, IOL Ng - Oncogenesis, 2022 - nature.com
Exosomes belong to a subpopulation of extracellular vesicles secreted by the dynamic
multistep endocytosis process and carry diverse functional molecular cargoes, including …

[HTML][HTML] Validation of miRNA prognostic power in hepatocellular carcinoma using expression data of independent datasets

Á Nagy, A Lánczky, O Menyhárt, B Győrffy - Scientific reports, 2018 - nature.com
Multiple studies suggested using different miRNAs as biomarkers for prognosis of
hepatocellular carcinoma (HCC). We aimed to assemble a miRNA expression database …

[HTML][HTML] Advances in the early diagnosis of hepatocellular carcinoma

W Wang, C Wei - Genes & diseases, 2020 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most prevalent cancers globally. In contrast to
the declining death rates observed for all other common cancers such as breast, lung, and …

Extracellular vesicles as biomarkers in liver diseases: A clinician's point of view

S Thietart, PE Rautou - Journal of hepatology, 2020 - Elsevier
Extracellular vesicles are membrane-bound vesicles containing proteins, lipids, RNAs and
microRNAs. They can originate from both healthy and stressed cells, and provide a …

[HTML][HTML] Non-exosomal and exosomal circulatory microRNAs: Which are more valid as biomarkers?

NNSB Nik Mohamed Kamal… - Frontiers in …, 2020 - frontiersin.org
MicroRNAs (miRNAs) are a group of small non-coding RNAs with approximately 19–25
nucleotides that are involved in regulating a range of developmental and physiological …

Recent advances in hepatocellular carcinoma therapy

R Dutta, RI Mahato - Pharmacology & therapeutics, 2017 - Elsevier
Hepatocellular carcinoma (HCC), also called malignant hepatoma, is one of the deadliest
cancers due to its complexities, reoccurrence after surgical resection, metastasis and …

Serum exosomal micro RNA s combined with alpha‐fetoprotein as diagnostic markers of hepatocellular carcinoma

Y Wang, C Zhang, P Zhang, G Guo, T Jiang… - Cancer …, 2018 - Wiley Online Library
Exosomal micro RNA s have recently been studied as the potential diagnostic marker for
various malignancies, including hepatocellular carcinoma (HCC). The aim of this study was …

In hepatocellular carcinoma miR-221 modulates sorafenib resistance through inhibition of caspase-3–mediated apoptosis

F Fornari, D Pollutri, C Patrizi, T La Bella, S Marinelli… - Clinical cancer …, 2017 - AACR
Purpose: The aberrant expression of miR-221 is a hallmark of human cancers, including
hepatocellular carcinoma (HCC), and its involvement in drug resistance, together with a …

[HTML][HTML] MiR-494 induces metabolic changes through G6pc targeting and modulates sorafenib response in hepatocellular carcinoma

C Bergamini, I Leoni, N Rizzardi, M Melli… - Journal of Experimental …, 2023 - Springer
Background Metabolic reprogramming is a well-known marker of cancer, and it represents
an early event during hepatocellular carcinoma (HCC) development. The recent approval of …

Exosomes, new biomarkers in early cancer detection

SH Jalalian, M Ramezani, SA Jalalian, K Abnous… - Analytical …, 2019 - Elsevier
Exosomes are endosomal-derived vesicles, playing a major role in cell-to-cell
communication. Multiple cells secret these vesicles to induce and inhibit different cellular …