Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training

B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

[HTML][HTML] The molecular athlete: exercise physiology from mechanisms to medals

R Furrer, JA Hawley, C Handschin - Physiological Reviews, 2023 - journals.physiology.org
Human skeletal muscle demonstrates remarkable plasticity, adapting to numerous external
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …

Physical activity and DNA methylation in humans

WJ Światowy, H Drzewiecka, M Kliber… - International journal of …, 2021 - mdpi.com
Physical activity is a strong stimulus influencing the overall physiology of the human body.
Exercises lead to biochemical changes in various tissues and exert an impact on gene …

Skeletal muscle memory

AP Sharples, DC Turner - American Journal of Physiology …, 2023 - journals.physiology.org
Skeletal muscle memory is an exciting phenomenon gaining significant traction across
several scientific communities, among exercise practitioners, and the public. Research has …

Genetic and epigenetic regulation of skeletal muscle ribosome biogenesis with exercise

VC Figueiredo, Y Wen, B Alkner… - The Journal of …, 2021 - Wiley Online Library
Key points Ribosome biogenesis and MYC transcription are associated with acute
resistance exercise (RE) and are distinct from endurance exercise in human skeletal muscle …

The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth

S Edman, RG Jones III, PR Jannig… - EMBO …, 2024 - embopress.org
A detailed understanding of molecular responses to a hypertrophic stimulus in skeletal
muscle leads to therapeutic advances aimed at promoting muscle mass. To decode the …

Epigenetic evidence for distinct contributions of resident and acquired myonuclei during long-term exercise adaptation using timed in vivo myonuclear labeling

KA Murach, CM Dungan… - American Journal of …, 2022 - journals.physiology.org
Muscle fibers are syncytial postmitotic cells that can acquire exogenous nuclei from resident
muscle stem cells, called satellite cells. Myonuclei are added to muscle fibers by satellite …

Exercise training modifies the whole blood DNA methylation profile in middle-aged and older women

G da Silva Rodrigues, NY Noronha… - Journal of Applied …, 2023 - journals.physiology.org
This is a longitudinal single-arm clinical trial aimed to investigate whether exercise training
would modify the whole blood methylation profile in healthy women. A total of 45 subjects …

[HTML][HTML] Dopamine in Sports: A Narrative Review on the Genetic and Epigenetic Factors Shaping Personality and Athletic Performance

K Humińska-Lisowska - International Journal of Molecular Sciences, 2024 - mdpi.com
This narrative review examines the relationship between dopamine-related genetic
polymorphisms, personality traits, and athletic success. Advances in sports genetics have …

[HTML][HTML] The 24-Hour Time Course of Integrated Molecular Responses to Resistance Exercise in Human Skeletal Muscle Implicates MYC as a Hypertrophic Regulator …

S Edman, RG Jones III, PR Jannig… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Molecular control of recovery after exercise in muscle is temporally dynamic. A time course
of biopsies around resistance exercise (RE) combined with-omics is necessary to better …