Aneuploidy, or imbalanced chromosome number, has profound effects on eukaryotic cells.
In humans, aneuploidy is associated with various pathologies, including cancer, which …

Regulated proteolysis is a vital process that affects all living things. Bacteria use energy-
dependent AAA+ proteases to power degradation of misfolded and native regulatory …

Toxin-antitoxin (TA) systems are ubiquitous genetic elements in bacterial genomes, but their
functions are controversial. Although they are frequently postulated to regulate cell growth …

Adaptive evolution is generally assumed to progress through the accumulation of beneficial
mutations. However, as deleterious mutations are common in natural populations, they …

To investigate the role of gene expression in adaptation of marine ectotherms to different
temperatures, we examined the transcriptome‐wide thermal stress response in …

First isolated and classified in the 1960s, Caulobacter crescentus has been instrumental in
the study of bacterial cell biology and differentiation. C. crescentus is a Gram-negative …

The α-proteobacterium Sinorhizobium meliloti establishes a chronic intracellular infection
during the symbiosis with its legume hosts. Within specialized host cells, S. meliloti …

Lon protease is a nuclear-encoded, mitochondrial ATP-dependent protease highly
conserved throughout the evolution, crucial for the maintenance of mitochondrial …

Toxin-antitoxin (TA) modules are bacterial regulatory switches that facilitate conflicting
outcomes for cells by promoting a pro-survival phenotypic adaptation and/or by directly …

Lon protease is a nuclear DNA-encoded mitochondrial enzyme highly conserved throughout
evolution, involved in the degradation of damaged and oxidized proteins of the …