Abstract The three‐dimensional (3D) multicellular platforms prepared by cells or
biomaterials have been widely applied in biomedical fields for the regeneration of complex …

Nervous system injuries remain a great challenge due to limited natural tissue regeneration
capabilities. Neural tissue engineering has been regarded as a promising approach for …

Peripheral nerve injuries may result in severe long-gap interruptions that are challenging to
repair. Autografting is the gold standard surgical approach for repairing long-gap nerve …

Spinal cord injury (SCI) treatment requires a nanosystem for drug delivery that can
effectively penetrate the blood–spinal cord barrier (BSCB). Herein, we designed poly (2 …

Demyelinating diseases involve loss of myelin sheaths and eventually lead to neurological
problems. Unfortunately, the precise mechanisms remain unknown, and there are no …

A hot topic in biomedical science is the implementation of more predictive in vitro models of
human tissues to significantly improve the knowledge of physiological or pathological …

The micro-or nanoscale surface morphology of the tissue engineering nerve guidance
scaffold (NGS) will affect different cell behaviors, such as their growth rate, migration, and …

Decellularized nerve hydrogels (dNHs) containing bioactive molecules are promising
biomaterials for peripheral nerve injury (PNI) treatment and have been extensively applied …

Surface modification of hydrophobic nanofibers (NFs) to introduce cell-interactive chemical
functionalities remains a challenge in biomedical applications. This study presents a novel …

Bioactive materials play vital roles in the repair of critical bone defects. However, bone tissue
engineering and regenerative medicine are still challenged by the need to repair bone …