[HTML][HTML] Alcohol consumption and metabolic syndrome: clinical and epidemiological impact on liver disease

F Åberg, CD Byrne, CJ Pirola, V Männistö… - Journal of …, 2023 - Elsevier
Alcohol use and metabolic syndrome are highly prevalent in the population and frequently
co-exist. Both are implicated in a large range of health problems, including chronic liver …

Information retrieval and text mining technologies for chemistry

M Krallinger, O Rabal, A Lourenco, J Oyarzabal… - Chemical …, 2017 - ACS Publications
Efficient access to chemical information contained in scientific literature, patents, technical
reports, or the web is a pressing need shared by researchers and patent attorneys from …

Computational tools for prioritizing candidate genes: boosting disease gene discovery

Y Moreau, LC Tranchevent - Nature Reviews Genetics, 2012 - nature.com
At different stages of any research project, molecular biologists need to choose—often
somewhat arbitrarily, even after careful statistical data analysis—which genes or proteins to …

Interactome mapping provides a network of neurodegenerative disease proteins and uncovers widespread protein aggregation in affected brains

C Haenig, N Atias, AK Taylor, A Mazza, MH Schaefer… - Cell reports, 2020 - cell.com
Interactome maps are valuable resources to elucidate protein function and disease
mechanisms. Here, we report on an interactome map that focuses on neurodegenerative …

PolySearch2: a significantly improved text-mining system for discovering associations between human diseases, genes, drugs, metabolites, toxins and more

Y Liu, Y Liang, D Wishart - Nucleic acids research, 2015 - academic.oup.com
Abstract PolySearch2 (http://polysearch. ca) is an online text-mining system for identifying
relationships between biomedical entities such as human diseases, genes, SNPs, proteins …

Candidate gene prioritization with Endeavour

LC Tranchevent, A Ardeshirdavani… - Nucleic acids …, 2016 - academic.oup.com
Genomic studies and high-throughput experiments often produce large lists of candidate
genes among which only a small fraction are truly relevant to the disease, phenotype or …

Genetics in non-alcoholic fatty liver disease: The role of risk alleles through the lens of immune response

S Sookoian, CJ Pirola - Clinical and Molecular Hepatology, 2022 - pmc.ncbi.nlm.nih.gov
The knowledge on the genetic component of non-alcoholic fatty liver disease (NAFLD) has
grown exponentially over the last 10 to 15 years. This review summarizes the current …

'Omics approaches to explore the breast cancer landscape

J Parsons, C Francavilla - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Breast cancer incidence is increasing worldwide with more than 600,000 deaths reported in
2018 alone. In current practice treatment options for breast cancer patients consists of …

The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo

T Maehara, H Mattoo, VS Mahajan… - Life science …, 2018 - life-science-alliance.org
Distinct T follicular helper (TFH) subsets that influence specific class-switching events are
assumed to exist, but the accumulation of isotype-specific TFH subsets in secondary …

DigSee: disease gene search engine with evidence sentences (version cancer)

J Kim, S So, HJ Lee, JC Park, J Kim… - Nucleic acids …, 2013 - academic.oup.com
Biological events such as gene expression, regulation, phosphorylation, localization and
protein catabolism play important roles in the development of diseases. Understanding the …