Influenza viruses have perplexed scientists for over a hundred years. Yearly vaccines limit
their spread, but they do not prevent all infections. Therapeutic treatments for those …

Abstract SARS-CoV-2, the virus causing COVID-19, has infected millions and has caused
hundreds of thousands of fatalities. Risk factors for critical illness from SARS-CoV-2 infection …

Viral infections are a major threat to the human population due to the lack of selective
therapeutic measures. The morbidity and mortality reported worldwide are very alarming …

Influenza epidemics and pandemics cause significant morbidity and mortality worldwide
associated with severe immunopathology in the lung, and the mechanisms of such …

In each influenza season, a distinct group of young, otherwise healthy individuals with no
risk factors succumbs to life-threatening infection. To better understand the cause for this, we …

Viral pneumonia is a major cause of acute respiratory distress syndrome (ARDS). Anti-
inflammatory therapies for viral-induced lung injury show promise in preclinical models …

The present review summarizes current knowledge on pathogenesis and clinical
manifestations of severe influenza. Immunological dysfunction during viral infection …

The host response to infection is known to be influenced by many factors, including genetics,
nutritional status, age, as well as drug and chemical exposures. Recent advances reveal …

Influenza is an annual, global healthcare concern. Secondary bacterial pneumonia is a
severe complication associated with primary influenza virus infection that often results in …

Influenza A viruses (IAVs) are highly contagious pathogens infecting human and numerous
animals. The viruses cause millions of infection cases and thousands of deaths every year …