Engineering biological nanopore approaches toward protein sequencing

X Wei, T Penkauskas, JE Reiner, C Kennard… - ACS …, 2023 - ACS Publications
Biotechnological innovations have vastly improved the capacity to perform large-scale
protein studies, while the methods we have for identifying and quantifying individual proteins …

Understanding and modelling the magnitude of the change in current of nanopore sensors

W Tang, JP Fried, RD Tilley, JJ Gooding - Chemical Society Reviews, 2022 - pubs.rsc.org
Nanopores are promising sensing devices that can be used for the detection of analytes at
the single molecule level. It is of importance to understand and model the current response …

Label-free optical detection of DNA translocations through plasmonic nanopores

DV Verschueren, S Pud, X Shi, L De Angelis… - ACS …, 2018 - ACS Publications
Solid-state nanopores are single-molecule sensors that hold great potential for rapid protein
and nucleic-acid analysis. Despite their many opportunities, the conventional ionic current …

Label-free detection of post-translational modifications with a nanopore

L Restrepo-Pérez, CH Wong, G Maglia, C Dekker… - Nano …, 2019 - ACS Publications
Post-translational modifications (PTMs) of proteins play key roles in cellular processes.
Hence, PTM identification is crucial for elucidating the mechanism of complex cellular …

Single-molecule fingerprinting of protein-drug interaction using a funneled biological nanopore

KB Jeong, M Ryu, JS Kim, M Kim, J Yoo… - Nature …, 2023 - nature.com
In drug discovery, efficient screening of protein-drug interactions (PDIs) is hampered by the
limitations of current biophysical approaches. Here, we develop a biological nanopore …

Lifetime and stability of silicon nitride nanopores and nanopore arrays for ionic measurements

YC Chou, P Masih Das, DS Monos, M Drndić - ACS nano, 2020 - ACS Publications
Nanopores are promising for many applications including DNA sequencing and molecular
filtration. Solid-state nanopores are preferable over their biological counterparts for …

Solid-state nanopores towards single-molecule DNA sequencing

Y Goto, R Akahori, I Yanagi, K Takeda - Journal of human genetics, 2020 - nature.com
Nanopore DNA sequencing offers a new paradigm owing to its extensive potential for long-
read, high-throughput detection of nucleotide modification and direct RNA sequencing …

Solvation‐involved nanoionics: new opportunities from 2D nanomaterial laminar membranes

H Zhan, Z Xiong, C Cheng, Q Liang, JZ Liu… - Advanced …, 2020 - Wiley Online Library
Nanoporous laminar membranes composed of multilayered 2D nanomaterials (2D‐NLMs)
are increasingly being exploited as a unique material platform for understanding solvated …

Biological nanopores: Engineering on demand

A Crnković, M Srnko, G Anderluh - Life, 2021 - mdpi.com
Nanopore-based sensing is a powerful technique for the detection of diverse organic and
inorganic molecules, long-read sequencing of nucleic acids, and single-molecule analyses …

Power generation by a pH-regulated conical nanopore through reverse electrodialysis

JP Hsu, SC Lin, CY Lin, S Tseng - Journal of Power Sources, 2017 - Elsevier
To assess the possibility of energy harvesting through reverse electrodialysis (RED), we
consider the electrokinetic behavior of the ion transport in a pH-regulated conical nanopore …