[HTML][HTML] Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

L Galluzzi, I Vitale, S Warren, S Adjemian… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune
response associated with immunological memory, provided they display sufficient …

Emerging roles of ATG7 in human health and disease

JJ Collier, F Suomi, M Oláhová… - EMBO molecular …, 2021 - embopress.org
The cardinal stages of macroautophagy are driven by core autophagy‐related (ATG)
proteins, whose ablation largely abolishes intracellular turnover. Disrupting ATG genes is …

[HTML][HTML] lncRNA SNHG11 promotes gastric cancer progression by activating the Wnt/β-catenin pathway and oncogenic autophagy

Q Wu, J Ma, J Wei, W Meng, Y Wang, M Shi - Molecular Therapy, 2021 - cell.com
Long non-coding RNAs (lncRNAs) are under active investigation in the development of
cancers, including gastric cancer (GC). Oncogenic autophagy is required for cancer cell …

Association of the epithelial–mesenchymal transition (EMT) with cisplatin resistance

M Ashrafizadeh, A Zarrabi, K Hushmandi… - International journal of …, 2020 - mdpi.com
Therapy resistance is a characteristic of cancer cells that significantly reduces the
effectiveness of drugs. Despite the popularity of cisplatin (CP) as a chemotherapeutic agent …

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Autophagy inhibitors for cancer therapy: small molecules and nanomedicines

JL Chen, X Wu, D Yin, XH Jia, X Chen, ZY Gu… - Pharmacology & …, 2023 - Elsevier
Autophagy is a conserved process in which the cytosolic materials are degraded and
eventually recycled for cellular metabolism to maintain homeostasis. The dichotomous role …

Anticancer mechanisms of metformin: A review of the current evidence

B Zhao, J Luo, T Yu, L Zhou, H Lv, P Shang - Life sciences, 2020 - Elsevier
Metformin, a US Food and Drug Administration-approved “star” drug used for diabetes
mellitus type 2, has become a topic of increasing interest to researchers due to its anti …

The role of autophagy in targeted therapy for acute myeloid leukemia

W Du, A Xu, Y Huang, J Cao, H Zhu, B Yang, X Shao… - Autophagy, 2021 - Taylor & Francis
Although molecular targeted therapies have recently displayed therapeutic effects in acute
myeloid leukemia (AML), limited response and acquired resistance remain common …

DNA-unresponsive platinum (II) complex induces ERS-mediated mitophagy in cancer cells

Y Guo, S Jin, H Yuan, T Yang, K Wang… - Journal of Medicinal …, 2021 - ACS Publications
Mitophagy is a selective autophagic process that degrades dysfunctional mitochondria.
Monofunctional platinum (II) complexes are candidates for anticancer drugs with the …

DGAT1 activity synchronises with mitophagy to protect cells from metabolic rewiring by iron depletion

M Long, A Sanchez‐Martinez, M Longo, F Suomi… - The EMBO …, 2022 - embopress.org
Mitophagy removes defective mitochondria via lysosomal elimination. Increased mitophagy
coincides with metabolic reprogramming, yet it remains unknown whether mitophagy is a …