Fecal microbiota transplantation as new therapeutic avenue for human diseases

M Biazzo, G Deidda - Journal of Clinical Medicine, 2022 - mdpi.com
The human body is home to a variety of micro-organisms. Most of these microbial
communities reside in the gut and are referred to as gut microbiota. Over the last decades …

The Bacterium Akkermansia muciniphila: A Sentinel for Gut Permeability and Its Relevance to HIV-Related Inflammation

J Ouyang, J Lin, S Isnard, B Fombuena… - Frontiers in …, 2020 - frontiersin.org
Gut dysbiosis, namely dysregulation of the intestinal microbiota, and increased gut
permeability lead to enhanced inflammation and are commonly seen in chronic conditions …

HIV-associated gut dysbiosis is independent of sexual practice and correlates with noncommunicable diseases

I Vujkovic-Cvijin, O Sortino, E Verheij, J Sklar… - Nature …, 2020 - nature.com
Loss of gut mucosal integrity and an aberrant gut microbiota are proposed mechanisms
contributing to chronic inflammation and increased morbidity and mortality during …

Fecal microbiota transplantation in HIV: A pilot placebo-controlled study

S Serrano-Villar, A Talavera-Rodríguez… - Nature …, 2021 - nature.com
Abstract Changes in the microbiota have been linked to persistent inflammation during
treated HIV infection. In this pilot double-blind study, we study 30 HIV-infected subjects on …

Candida albicans can foster gut dysbiosis and systemic inflammation during HIV infection

SD Zaongo, J Ouyang, S Isnard, X Zhou… - Gut …, 2023 - Taylor & Francis
Candida albicans (C. albicans) is a ubiquitous fungal commensal component of the human
microbiota, and under certain circumstances, such as during an immunocompromised state …

Gut Bacteroides act in a microbial consortium to cause susceptibility to severe malaria

RK Mandal, A Mandal, JE Denny, R Namazii… - Nature …, 2023 - nature.com
Malaria is caused by Plasmodium species and remains a significant cause of morbidity and
mortality globally. Gut bacteria can influence the severity of malaria, but the contribution of …

From dysbiosis to defense: harnessing the gut microbiome in HIV/SIV therapy

JM Brenchley, S Serrano-Villar - Microbiome, 2024 - Springer
Background Although the microbiota has been extensively associated with HIV
pathogenesis, the majority of studies, particularly those using omics techniques, are largely …

Differential effects of antiretroviral treatment on immunity and gut microbiome composition in people living with HIV in rural versus urban Zimbabwe

AS Burkhart Colorado, A Lazzaro, CP Neff… - Microbiome, 2024 - Springer
Background The widespread availability of antiretroviral therapy (ART) has dramatically
reduced mortality and improved life expectancy for people living with HIV (PLWH). However …

[HTML][HTML] Pathogenesis of aging and age-related comorbidities in people with HIV: highlights from the HIV ACTION workshop

D Gabuzda, BD Jamieson, RG Collman… - Pathogens and …, 2020 - ncbi.nlm.nih.gov
People with HIV (PWH) experience accentuated biological aging, as defined by markers of
inflammation, immune dysfunction, and the epigenetic clock. They also have an elevated …

The metabolic consequences of HIV/TB co-infection

C Herbert, L Luies, DT Loots, AA Williams - BMC Infectious Diseases, 2023 - Springer
Background The synergy between the human immunodeficiency virus (HIV) and
Mycobacterium tuberculosis during co-infection of a host is well known. While this synergy is …