Alternative splicing (AS) of RNA molecules is a key contributor to transcriptome diversity. In
humans, 90%–95% of multi-exon genes produce alternatively spliced RNA transcripts …

As ubiquitously expressed transcripts in eukaryotes, circular RNAs (circRNAs) are covalently
closed and lack a 5′-cap and 3′-polyadenylation (poly (A)) tail. Initially, circRNAs were …

Background LINC-PINT was downregulated in nasopharyngeal carcinoma (NPC) and
correlated with treatment efficiency of NPC. However, the underlying mechanism of LINC …

Long noncoding RNAs (lncRNAs) possess the potential for therapeutic targeting to treat
many disorders, including cancers. Several RNA-based therapeutics (ASOs and small …

Resistance to cisplatin (DDP) is a major obstacle in the clinical treatment of advanced
gastric cancer (GC). Long noncoding RNA (lncRNA) play a significant regulatory role in the …

Cancer as a progressive and complex disease is caused by early chromosomal changes
and stimulated cellular transformation. Previous studies reported that long non-coding RNAs …

According to estimates, cancer will be the leading cause of death globally in 2022,
accounting for 9.6 million deaths. At present, the three main therapeutic modalities utilized to …

Cyclin-dependent kinases (CDKs) regulate cell division at multiple levels. Aberrant
proliferation induced by abnormal cell cycle is a hallmark of cancer. Over the past few …

Long non-coding (lnc) RNAs, once considered as junk and useless, are now broadly
recognized to have major functions in the cell. LncRNAs are defined as non-coding RNAs of …

Objectives Esophageal squamous cell carcinoma (ESCC) is a malignant tumor with high
incidence and mortality rates worldwide. This study aimed to investigate the correlation …