Despite over 50 years of research, the field of sports nutrition continues to grow at a rapid
rate. Whilst the traditional research focus was one that centred on strategies to maximise …

To enhance glucose uptake into muscle and fat cells, insulin stimulates the translocation of
GLUT4 glucose transporters from intracellular membranes to the cell surface. This response …

AMPK is an evolutionary conserved sensor of cellular energy status that is activated during
exercise. Pharmacological activation of AMPK promotes glucose uptake, fatty acid oxidation …

Purpose The aim of this study was to determine the early time course of exercise-induced
signaling after divergent contractile activity associated with resistance and endurance …

The purpose of this review is to provide information about the role of exercise in the
prevention of skeletal muscle insulin resistance, that is, the inability of insulin to properly …

This review focuses on two paralogue Rab GTPase activating proteins known as TBC1D1
Tre-2/BUB2/cdc 1 domain family (TBC1D) 1 and TBC1D4 (also called Akt Substrate of 160 …

We examined acute molecular responses in skeletal muscle to divergent exercise stimuli by
combining consecutive bouts of resistance and endurance exercise. Eight men [22.9±6.3 yr …

Key points Phosphorylation signature patterns on TBC1D1 and TBC1D4 proteins in the
insulin–glucose pathway were investigated in human skeletal muscle in response to …

To elucidate the molecular mechanisms behind physical inactivity–induced insulin
resistance in skeletal muscle, 12 young, healthy male subjects completed 7 days of bed rest …

The mammalian target of rapamycin (mTOR) is a highly conserved atypical serine–threonine
kinase that controls numerous functions essential for cell homeostasis and adaptation in …