Globally, breast cancer is the most frequently diagnosed cancer among women. The major
unresolved problems with metastatic breast cancer is recurrence after receiving objective …

Anthracyclines (doxorubicin, daunorubicin, epirubicin, and idarubicin) are currently the most
effective group of anti-neoplastic drugs used in clinical practice. Of these, doxorubicin (also …

Clinical and animal studies have demonstrated that chemotherapeutic doxorubicin (DOX)
increases arterial stiffness, a predictor of cardiovascular risk. Despite consensus about DOX …

Cancer-related fatigue is a pervasive syndrome experienced by a majority of cancer patients
undergoing treatment, and muscular dysfunction may be a key component in the …

Cancer is one of the leading causes of deaths worldwide with 18.1 million deaths per year.
Although there have been significant advances in anti-cancer therapies, they can often …

Arterial stiffness is an important predictor of cardiovascular risk. Clinical studies have
demonstrated that arterial stiffness increases in cancer patients treated with the …

Introduction Chemotherapy may induce deleterious effects in normal tissues, leading to
organ damage. Direct vascular injury is the least characterized side effect. Our aim was to …

Doxorubicin (DOX) is a chemotherapeutic agent used for treatment of different cancers and
its clinical usage is hindered by the oxidative injury-related cardiotoxicity. This work aims to …

Vincristine is an effective anticancer agent for treating leukemias, lymphomas, and other
solid tumors. Vincristine's better-known severe side effects include bone marrow depression …

Cardiovascular diseases (CVD) are the leading cause of death worldwide, and age is by far
the greatest risk factor for developing CVD. Vascular dysfunction, including endothelial …