Towards more tolerable subcutaneous administration: Review of contributing factors for improving combination product design

N Mathias, S Huille, M Picci, RP Mahoney… - Advanced Drug Delivery …, 2024 - Elsevier
Subcutaneous (SC) injections can be associated with local pain and discomfort that is
subjective and may affect treatment adherence and overall patient experience. With …

The mechanisms and management of persistent postsurgical pain

AM Fuller, S Bharde, S Sikandar - Frontiers in Pain Research, 2023 - frontiersin.org
An estimated 10%–50% of patients undergoing a surgical intervention will develop
persistent postsurgical pain (PPP) lasting more than 3 months despite adequate acute pain …

[HTML][HTML] No place for routine use of modified-release opioids in postoperative pain management

J Quinlan, N Levy, DN Lobo, PE Macintyre - British Journal of Anaesthesia, 2022 - Elsevier
Modified-release opioid tablets were introduced into surgical practice in the belief that they
provided superior pain relief and reduced nursing workload, and they rapidly became …

Methodological quality of 100 recent systematic reviews of health-related outcome measurement instruments: an overview of reviews

EBM Elsman, LB Mokkink, IL Abma, OL Aiyegbusi… - Quality of Life …, 2024 - Springer
Purpose Systematic reviews evaluating and comparing the measurement properties of
outcome measurement instruments (OMIs) play an important role in OMI selection. Earlier …

[HTML][HTML] Intraoperative pharmacologic opioid minimisation strategies and patient-centred outcomes after surgery: a scoping review

M Verret, NH Lam, M Lalu, SG Nicholls… - British Journal of …, 2024 - Elsevier
Background Postoperative patient-centred outcome measures are essential to capture the
patient's experience after surgery. Although a large number of pharmacologic opioid …

Opioid prescribing for acute postoperative pain: an overview of systematic reviews related to two consensus statements relevant at patient, prescriber, system and …

CL McCorquodale, R Greening, R Tulloch, P Forget - BMC anesthesiology, 2023 - Springer
Background National guidelines for rational opioid prescribing for acute postoperative pain
are needed to optimise postoperative pain control and function whilst minimising opioid …

[HTML][HTML] Correlation between Harris hip score and gait analysis through artificial intelligence pose estimation in patients after total hip arthroplasty

SY Lee, SJ Park, JA Gim, YJ Kang, SH Choi… - Asian Journal of …, 2023 - Elsevier
Background Recently, open pose estimation using artificial intelligence (AI) has enabled the
analysis of time series of human movements through digital video inputs. Analyzing a …

Early feasibility of an activity-based intervention for improving ingestive functions in older adults with oropharyngeal dysphagia

T Hansen, LB Laursen, MS Hansen - Geriatrics, 2023 - mdpi.com
There is growing awareness about the use of combined strength-and skill-based swallowing
training for improving swallowing physiology in the event of dysphagia. Such an approach …

The prescribed opioid crisis as an impetus to improve postoperative pain management.

A Simpson, E Keane, N Levy - Anaesthesia, 2023 - search.ebscohost.com
In addition, those patients taking modified-release opioids in the 6 months preceding
surgery had an odds ratio of 3.5 for developing persistent postoperative opioid use; …

Peri‐operative pain management in adults: a multidisciplinary consensus statement from the Association of Anaesthetists and the British Pain Society

K El‐Boghdadly, NA Levy, WJ Fawcett… - …, 2024 - Wiley Online Library
Background Nearly half of adult patients undergoing surgery experience moderate or severe
postoperative pain. Inadequate pain management hampers postoperative recovery and …