Regeneration of bone defects caused by trauma, infection, tumours or inherent genetic
disorders is a clinical challenge that usually necessitates bone grafting materials …

Repairing large bone defects caused by severe trauma or tumor resection remains one of
the major challenges in orthopedics and maxillofacial surgery. A promising therapeutic …

Immune reactions are a key factor in determining the destiny of bone substitute materials
after implantation. Macrophages, the most vital factor in the immune response affecting …

The recognition and importance of immune cells during bone regeneration, including
around bone biomaterials, has led to the development of an entire field termed …

Physicians are aware of the benefits of calcium and vitamin D supplementation. However,
additional nutritional components may also be important for bone health. There is a growing …

Implant-related infection of biomaterials is one of the main causes of arthroplasty and
osteosynthesis failure. Bacteria, such as the rapidly-emerging Multi Drug Resistant (MDR) …

This study aimed to evaluate the effectiveness of sonochemical and milling nanoparticulate
techniques using HA of bovine origin. The starting powders were characterized using X-ray …

Dental caries is the most prevalent infectious oral disease experienced by more than 90% of
adults in the United States. 1, 2 A quarter of US populations do not have dental insurance, 3 …

Silica and collagen are two of the most abundant substances in the Earth's geosphere and
biosphere, respectively. Yet, their close association in nature has never been clearly …

Historically, silicon has been accorded low importance as a trace element. Its role has
generally been regulated to that of minor influence on bone and connective tissue …