Campylobacter jejuni is the leading cause of bacterial diarrhoeal disease in many areas of
the world. The high incidence of sporadic cases of disease in humans is largely due to its …

Bacterial enhancer binding proteins (bEBPs) are transcriptional activators that assemble as
hexameric rings in their active forms and utilize ATP hydrolysis to remodel the conformation …

Maintaining the faithful flow of information through signal transduction pathways is critical to
the survival and proliferation of organisms. This problem is particularly challenging as many …

The Enterobacter cloacae complex (ECC) consists of closely related bacteria commonly
associated with the human microbiota. ECC are increasingly isolated from healthcare …

Campylobacter jejuni promotes commensalism in the intestinal tracts of avian hosts and
diarrheal disease in humans, yet components of intestinal environments recognized as …

For a generation of microbiologists who study pathogenesis in the context of the human
microbiome, understanding the diversity of bacterial metabolism is essential. In this chapter …

Campylobacter jejuni is one of the leading infectious causes of food-borne illness around
the world. Its ability to persistently colonize the intestinal tract of a broad range of hosts …

Highlights•Kinase bifunctionality and feedback loops produce complex temporal
dynamics.•Many two-component pathways exhibit partial adaptation or pulsing behavior.• …

The flagellum of Campylobacter jejuni provides motility essential for commensal
colonization of the intestinal tract of avian species and infection of humans resulting in …

Two-component signaling systems (TCSs) are composed of two proteins, sensor kinases
and response regulators, which can cross-talk and integrate information between them by …