As a phenolic acid compound, caffeic acid (CA) can be isolated from different sources such
as tea, wine and coffee. Caffeic acid phenethyl ester (CAPE) is naturally occurring derivative …

Prostate cancer is among most malignant tumors around the world and this urological tumor
can be developed as result of genomic mutations and their accumulation during progression …

Novel tolmetin derivatives 5a–f to 8a–c were designed, synthesised, and evaluated for
antiproliferative activity by NCI (USA) against a panel of 60 tumour cell lines. The cytotoxic …

A comprehensive summary of more than 450 estrogenic chemicals including estrogenic
endocrine disruptors is provided here to understand the complex and profound impact of …

Prostate cancer is the most prevalent disease affecting males in many Western countries,
with an estimated 29,480 deaths in 2014 in the US alone. Incidence rates for prostate cancer …

Multi-target inhibitors represent useful anticancer agents with superior therapeutic attributes.
Here in, two novel series of benzimidazole-triazole hybrids were designed, synthesised as …

Propolis is a bee-metabolized resinous substance (bee glue) from plant sap and gums. It
has been in usage as a healing agent since antiquity, yet has not garnered global popularity …

A series of novel hybrid compounds of hexahydrobenzo [4, 5] thieno [2, 3-d] pyrimidine with
aminothiazole scaffolds were synthesized. The synthesized compounds were evaluated for …

Nutrigenomics effects have an important role in the manipulation of dietary components for
human benefit, particularly in cancer prevention or treatment. The impact of dietary …

Doxorubicin (Dox), an effective anticancer agent, can impair testicular function leading to
infertility. The present study aimed to explore the protective effect of propolis extract on Dox …