Conversion of glucose into glycogen is a major pathway that contributes to the removal of
glucose from the portal vein by the liver in the postprandial state. It is regulated in part by the …

Liver glycogen is synthesized after a meal in response to an increase in blood glucose
concentration in the portal vein and endocrine and neuroendocrine signals, and is degraded …

Glucose is an energy source that also controls the expression of key genes involved in
energetic metabolism through the glucose-signaling transcription factor carbohydrate …

Abstract Nrf2 (NF-E2-related factor 2) contributes to the maintenance of glucose
homeostasis in vivo. Nrf2 suppresses blood glucose levels by protecting pancreatic β cells …

Most cancer cells exhibit an accelerated glycolysis rate compared to normal cells. This
metabolic change is associated with the over-expression of all the pathway enzymes and …

Insulin governs systemic glucose metabolism, including glycolysis, gluconeogenesis and
glycogenesis, through temporal change and absolute concentration. However, how insulin …

Circadian rhythms play a critical role in regulating metabolism, including daily cycles of
feeding/fasting. Glucokinase (GCK) is central for whole-body glucose homeostasis and …

Abstract Purpose of Review Increased glucose production associated with hepatic insulin
resistance contributes to the development of hyperglycemia in T2D. The molecular …

Background Epidemiological studies have reported that the prevalence of diabetes in
women> 40 years of age, especially those in the postmenopausal phase, was higher than in …

Glucagon rapidly and profoundly stimulates hepatic glucose production (HGP), but for
reasons that are unclear, this effect normally wanes after a few hours, despite sustained …