Phthalate metabolites: Characterization, toxicities, global distribution, and exposure assessment

YJ Zhang, JL Guo, J Xue, CL Bai, Y Guo - Environmental Pollution, 2021 - Elsevier
Phthalates are plasticizers in various products and regarded as endocrine disruptors due to
their anti-androgen effects. Environmental occurrence and toxicities of parent phthalates …

[HTML][HTML] The impact of Di-(2-ethylhexyl) Phthalate and Mono (2-ethylhexyl) Phthalate in placental development, function, and pathophysiology

LD Martínez-Razo, A Martínez-Ibarra… - Environment …, 2021 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP) is a chemical widely distributed in the
environment as is extensively used in the plastic industry. DEHP is considered an endocrine …

An insight into sex-specific neurotoxicity and molecular mechanisms of DEHP: a critical review

Y Liu, Z Guo, R Zhu, D Gou, PP Jia, DS Pei - Environmental Pollution, 2023 - Elsevier
Abstract Di-2-Ethylhexyl Phthalate (DEHP) is often used as an additive in polyvinyl chloride
(PVC) to give plastics flexibility, which makes DEHP widely used in food packaging, daily …

Impacts of bisphenol A (BPA) and phthalate exposures on epigenetic outcomes in the human placenta

RS Strakovsky, SL Schantz - Environmental epigenetics, 2018 - academic.oup.com
The placenta guides fetal growth and development. Bisphenol A (BPA) and phthalates are
widespread environmental contaminants and endocrine disruptors, and the placental …

The promises and challenges of toxico-epigenomics: environmental chemicals and their impacts on the epigenome

FFL Chung, Z Herceg - Environmental Health Perspectives, 2020 - ehp.niehs.nih.gov
Background: It has been estimated that a substantial portion of chronic and
noncommunicable diseases can be caused or exacerbated by exposure to environmental …

Distribution of micro-nano PS, DEHP, and/or MEHP in mice and nerve cell models in vitro after exposure to micro-nano PS and DEHP

J Han, J Yan, K Li, B Lin, W Lai, L Bian, R Jia, X Liu… - Toxics, 2023 - mdpi.com
Polystyrene (PS) and di-(2-ethylhexyl) phthalate (DEHP) exist widely in the environment.
However, their distribution in organisms remains unclear. We used three sizes (50 nm, 500 …

Simultaneous detection of tumor cell apoptosis regulators Bcl-2 and Bax through a dual-signal-marked electrochemical immunosensor

S Zhou, Y Wang, JJ Zhu - ACS Applied Materials & Interfaces, 2016 - ACS Publications
B-cell lymphoma 2 (Bcl-2) and Bcl-2-associated X protein (Bax) are often used to monitor the
apoptosis of tumor cells and evaluate cancer drug effect. In this work, a novel sandwich-type …

Exposure to endocrine disrupting chemicals impacts immunological and metabolic status of women during pregnancy

AK Merrill, M Sobolewski, M Susiarjo - Molecular and Cellular …, 2023 - Elsevier
Pregnancy is a unique physiological window for maternal and fetal health. Disorders that
arise during pregnancy influence the survival and health outcomes of mother and baby …

Gestational bisphenol S impairs placental endocrine function and the fusogenic trophoblast signaling pathway

J Gingrich, Y Pu, J Roberts, R Karthikraj, K Kannan… - Archives of …, 2018 - Springer
Exposure to bisphenolic chemicals during pregnancy occurs in> 90% of pregnancies.
Bisphenolic compounds can cross the placental barrier reaching fetal circulation. However …

Placental outcomes of phthalate exposure

GR Warner, RS Dettogni, IC Bagchi, JA Flaws… - Reproductive …, 2021 - Elsevier
Proper placental development and function relies on hormone receptors and signaling
pathways that make the placenta susceptible to disruption by endocrine disrupting …