Introduction Evidence-based recommendations are needed to guide the acute management
of the bleeding trauma patient. When these recommendations are implemented patient …

The aims of severe perioperative bleeding management are three-fold. First, preoperative
identification by anamesis and laboratory testing of those patients for whom the …

Introduction The appropriate strategy for trauma-induced coagulopathy management is
under debate. We report the treatment of major trauma using mainly coagulation factor …

Plasma utilization has increased over the past two decades, and there is a growing concern
that many plasma transfusions are inappropriate. Plasma transfusion is not without risk, and …

The effect of pregabalin on oxycodone consumption, post-operative confusion, and pain in
elderly cardiac surgery patients was investigated in a prospective, randomized, doubleblind …

Fluid resuscitation after massive hemorrhage in major surgery and trauma may result in
extensive hemodilution and coagulopathy, which is of a multifactorial nature. Although …

Fibrinogen plays several key roles in the maintenance of hemostasis. Its cleavage by
thrombin and subsequent polymerization to form fibrin strands provides the structural …

Introduction Thromboelastometry (TEM)-guided haemostatic therapy with fibrinogen
concentrate and prothrombin complex concentrate (PCC) in trauma patients may reduce the …

Methods: Our institution's exsanguination protocol (TEP) involves the immediate delivery of
products in a 3: 2 ratio of RBC: FFP and 5: 1 for RBC: platelets. All patients receiving TEP …

Objectives: Cardiac surgery, including coronary artery bypass, cardiac valve, and aortic
procedures, is among the most common surgical procedures performed in the United States …